GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

Category:GO:1990270 ! platelet-derived growth factor receptor-ligand complex

From GONUTS
Jump to: navigation, search

DAG for GO:1990270id: GO:1990270

name: platelet-derived growth factor receptor-ligand complex
namespace: cellular_component
def: "A tetrameric protein complex consisting of two platelet-derived growth factor (PDGF) receptor subunits and two PDGF ligand subunits. Binding of the PDGF ligand dimer to the PDGF receptor in the plasma membrane induces receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes and are found in all vertebrates. At least two different receptor chains (A and B) and four types of ligand chains (A, B, C, and D) are known forming a wide variety of combinations of receptor-ligand complexes." [GOC:bhm, PMID:11331882]
comment: An example of this is PDGFA-PGFRA in human (UniProt symbols P04085, P16234) in PMID:7679113 (inferred from direct assay).
synonym: "PDGF complex" BROAD []
synonym: "PDGF receptor-ligand complex" EXACT []
synonym: "PDGF-AA-receptor alpha complex" NARROW []
synonym: "PDGF-AB-receptor alpha complex" NARROW []
synonym: "PDGF-AB-receptor beta complex" NARROW []
synonym: "PDGF-BB-receptor alpha complex" NARROW []
synonym: "PDGF-BB-receptor alpha-beta complex" NARROW []
synonym: "PDGF-BB-receptor beta complex" NARROW []
synonym: "PDGF-CC-receptor alpha complex" NARROW []
synonym: "PDGF-CC-receptor alpha-beta complex" NARROW []
synonym: "PDGF-CC-receptor beta complex" NARROW []
synonym: "PDGF-DD-receptor alpha-beta complex" NARROW []
synonym: "PDGF-DD-receptor beta complex" NARROW []
synonym: "receptor-ligand complex" BROAD []
is_a: GO:0098797 ! plasma membrane protein complex
relationship: has_part: GO:0043235 ! receptor complex
relationship: has_part: GO:1990265 ! platelet-derived growth factor complex
relationship: part_of: GO:0005887 ! integral component of plasma membrane

AmiGO <GOterm>GO:1990270</GOterm>
Gene Ontology Home


The contents of this box are automatically generated. You can help by adding information to the "Notes"

Usage Notes

References

See Help:References for how to manage references in GONUTS.

This category currently contains no pages or media.