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Category:GO:0098535 ! de novo centriole assembly involved in multi-ciliated epithelial cell differentiation

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DAG for GO:0098535id: GO:0098535

name: de novo centriole assembly involved in multi-ciliated epithelial cell differentiation
namespace: biological_process
def: "Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation." [GOC:cilia, GOC:dos, PMID:24075808, PMID:5111878, PMID:5661997]
comment: In most eukaryotic cells, 'centriole' (GO:0005814) and 'ciliary basal body' (GO:0036064) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component.
synonym: "centriole amplification" RELATED [PMID:24075808]
synonym: "de novo centriole assembly" BROAD []
synonym: "de novo centriole assembly via deuterosome" EXACT []
synonym: "deuterosomal basal body biogenesis" RELATED []
synonym: "deuterosome pathway" RELATED [PMID:25047614]
synonym: "deuterosome-mediated centriole biogenesis" RELATED [PMID:24075808]
synonym: "multiciliation" RELATED []
synonym: "multiciliogenesis" RELATED []
is_a: GO:0097742 ! de novo centriole assembly
relationship: part_of: GO:1903251 ! multi-ciliated epithelial cell differentiation
intersection_of: GO:0097742 ! de novo centriole assembly
intersection_of: part_of GO:1903251 ! multi-ciliated epithelial cell differentiation

AmiGO <GOterm>GO:0098535</GOterm>
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