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Category:GO:0097199 ! cysteine-type endopeptidase activity involved in apoptotic signaling pathway

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DAG for GO:0097199id: GO:0097199

name: cysteine-type endopeptidase activity involved in apoptotic signaling pathway
namespace: molecular_function
def: "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway." [GOC:mtg_apoptosis, PMID:11717445, Wikipedia:Caspase]
comment: Examples of gene products that may be annotated to this term include CASP2, CASP8, CASP9, and CASP10, also called initiator (or apical, or activator) caspases.
synonym: "activator caspase activity" NARROW []
synonym: "apical caspase activity" NARROW []
synonym: "cysteine-type endopeptidase activity involved in apoptotic signalling pathway" EXACT [GOC:mah]
synonym: "initiator caspase activity" NARROW []
is_a: GO:0097153 ! cysteine-type endopeptidase activity involved in apoptotic process
relationship: part_of: GO:0097190 ! apoptotic signaling pathway
intersection_of: GO:0004197 ! cysteine-type endopeptidase activity
intersection_of: part_of GO:0097190 ! apoptotic signaling pathway

AmiGO <GOterm>GO:0097199</GOterm>
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Pages in category "GO:0097199 ! cysteine-type endopeptidase activity involved in apoptotic signaling pathway"

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