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Category:GO:0090625 ! mRNA destabilization-mediated gene silencing by siRNA

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DAG for GO:0090625id: GO:0090625

name: mRNA destabilization-mediated gene silencing by siRNA
namespace: biological_process
def: "The process in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:15260970]
synonym: "mRNA cleavage involved in gene silencing by siRNA" EXACT []
is_a: GO:0035194 ! post-transcriptional gene silencing by RNA
is_a: GO:0098795 ! mRNA destabilization-mediated gene silencing

AmiGO <GOterm>GO:0090625</GOterm>
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