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Category:GO:0090489 ! L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)

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DAG for GO:0090489id: GO:0090489

name: L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)
namespace: molecular_function
def: "Catalyzes the multi-step reaction: L-Tryptophan + 2 Oxygen + 2 NADPH + 2 H+ = Indole-3-acetaldehyde oxime + 3 H2O + 2 NADP+ + CO2. The individual reactions are: (1a) L-tryptophan + O2 + NADPH + H+ = N-hydroxy-L-tryptophan + NADP+ + H2O,(1b) N-hydroxy-L-tryptophan + O2 + NADPH + H+ = N,N-dihydroxy-L-tryptophan + NADP+ + H2O, and (1c) N,N-dihydroxy-L-tryptophan = (E)-indol-3-ylacetaldoxime + CO2 + H2O." [EC:, KEGG:R08160]
synonym: "tryptophan N-monooxygenase activity" RELATED []
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
relationship: has_part: GO:0090490 ! L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)
relationship: has_part: GO:0090491 ! N-hydroxy-L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)
relationship: has_part: GO:0090492 ! N,N-Dihydroxy-L-tryptophan decarboxylase activity


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