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Category:GO:0071012 ! catalytic step 1 spliceosome
name: catalytic step 1 spliceosome
namespace: cellular_component
def: "A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs." [GOC:ab, GOC:krc, GOC:mah, PMID:18322460, PMID:19239890]
synonym: "activated spliceosome" EXACT [GOC:krc, ISBN:0879695897, ISBN:0879697393]
synonym: "mammalian spliceosomal complex B*" NARROW [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890]
synonym: "mammalian spliceosomal complex B2" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393]
synonym: "yeast spliceosomal complex A1" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393]
is_a: GO:0005681 ! spliceosomal complex
is_a: GO:1902494 ! catalytic complex
relationship: has_part: GO:0000974 ! Prp19 complex
relationship: has_part: GO:0005682 ! U5 snRNP
AmiGO
<GOterm>GO:0071012</GOterm>
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This category has the following 2 subcategories, out of 2 total.
