name: U2-type precatalytic spliceosome
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def: "A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs." [GOC:ab, GOC:krc, GOC:mah, PMID:18322460, PMID:19239890]
synonym: "GT-AG precatalytic spliceosome" NARROW [GOC:krc, GOC:mah]
synonym: "major precatalytic spliceosome" EXACT [GOC:krc, GOC:mah]
synonym: "mammalian U2-type spliceosomal complex B" NARROW [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890]
synonym: "mammalian U2-type spliceosomal complex B1" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393]
synonym: "yeast U12-type spliceosomal complex A2-1" RELATED [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393]
is_a: GO:0005684 ! U2-type spliceosomal complex
is_a: GO:0071011 ! precatalytic spliceosome
relationship: has_part: GO:0005685 ! U1 snRNP
relationship: has_part: GO:0005686 ! U2 snRNP
relationship: has_part: GO:0046540 ! U4/U6 x U5 tri-snRNP complex
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Pages in category "GO:0071005 ! U2-type precatalytic spliceosome"
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