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Category:GO:0062176 ! R-loop processing
name: R-loop processing
namespace: biological_process
def: "A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability." [PMID:27252122, PMID:28790157, PMID:33986538]
synonym: "R-loop disassembly" EXACT []
is_a: GO:0006338 ! chromatin remodeling
AmiGO
<GOterm>GO:0062176</GOterm>
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