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Category:GO:0047101 ! branched-chain alpha-keto acid dehydrogenase activity

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DAG for GO:0047101id: GO:0047101

name: branched-chain alpha-keto acid dehydrogenase activity
namespace: molecular_function
def: "Catalysis of the reaction: [a branched-chain alpha-keto acid] + CoA + NAD+ = [a branched-chain acyl-CoA] + CO2 + NADH. This enzyme system catalyzes the oxidative decarboxylation of branched-chain alpha-keto acids derived from L-leucine, L-isoleucine, and L-valine to branched-chain acyl-CoAs." [EC:1.2.1.25]
synonym: "2-oxoisovalerate dehydrogenase (acylating) activity" NARROW [EC:1.2.1.25]
synonym: "2-oxoisovalerate dehydrogenase activity" RELATED [EC:1.2.1.25]
synonym: "3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating)" RELATED [EC:1.2.1.25]
xref: EC:1.2.1.25
xref: MetaCyc:1.2.1.25-RXN
is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

AmiGO <GOterm>GO:0047101</GOterm>
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