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Category:GO:0045122 ! aflatoxin biosynthetic process
name: aflatoxin biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450." [ISBN:0716731363, ISBN:0815316194, PMID:15006741]
synonym: "aflatoxin anabolism" EXACT []
synonym: "aflatoxin biosynthesis" EXACT []
synonym: "aflatoxin formation" EXACT []
synonym: "aflatoxin synthesis" EXACT []
is_a: GO:0006083 ! acetate metabolic process
is_a: GO:0043386 ! mycotoxin biosynthetic process
is_a: GO:0046222 ! aflatoxin metabolic process
is_a: GO:1901378 ! organic heteropentacyclic compound biosynthetic process
relationship: has_part: GO:0004321 ! fatty-acyl-CoA synthase activity
relationship: has_part: GO:0042469 ! versicolorin reductase activity
relationship: has_part: GO:0046572 ! versicolorin B synthase activity
relationship: has_part: GO:0047145 ! demethylsterigmatocystin 6-O-methyltransferase activity
relationship: has_part: GO:0047146 ! sterigmatocystin 7-O-methyltransferase activity
relationship: has_part: GO:0102973 ! norsolorinate anthrone synthase activity
relationship: has_part: GO:0140393 ! norsolorinic acid ketoreductase activity
relationship: has_part: GO:0140395 ! averantin hydroxylase activity
relationship: has_part: GO:0140396 ! 5'-hydroxyaverantin dehydrogenase activity
relationship: has_part: GO:0140397 ! versiconal hemiacetal acetate esterase activity
relationship: has_part: GO:0140398 ! versicolorin B desaturase activity
relationship: has_part: GO:0140399 ! aflatoxin B synthase activity
AmiGO
<GOterm>GO:0045122</GOterm>
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This category has the following 4 subcategories, out of 4 total.
