name: ATPase activity, uncoupled
def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction is not directly coupled to any other reaction." [EC:18.104.22.168, PMID:12912988]
comment: An example of this activity is found in brown adopise tissue, where an isoform of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) is capable of ATPase activity not coupled to Ca2+ transport in a reaction that is more thermogenic than the coupled reaction (PMID:12912988).
synonym: "adenylpyrophosphatase activity" RELATED [EC:22.214.171.124]
is_a: GO:0016887 ! ATPase activity
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