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Category:GO:0040033 ! sRNA-mediated post-transcriptional gene silencing
name: sRNA-mediated post-transcriptional gene silencing
namespace: biological_process
def: "A post-transcriptional gene silencing pathway mediated by the action of small regulatory non-coding RNAs (sRNAs). sRNAs are 20-500 nucleotides in length and found in bacteria." [PMID:12460531, PMID:2468565, PMID:33963446]
comment: It is postulated that there 3 mechanisms of sRNA-mediated gene silencing: (i) translation inhibition, (ii) RNA destabilization, and (iii) transcription termination loop formation (as this is common when looking at riboswitches). sRNA mediated gene silencing is sometimes referred to as 'regulation of riboswitch'.
subset: goslim_prokaryote
synonym: "downregulation of mRNA translation, ncRNA-mediated" BROAD []
synonym: "inhibition of mRNA translation, ncRNA-mediated" BROAD []
synonym: "RNA-mediated gene silencing by inhibition of translation" BROAD []
synonym: "small RNA-mediated gene silencing" EXACT []
synonym: "sRNA-mediated gene silencing" BROAD []
is_a: GO:0035194 ! regulatory ncRNA-mediated post-transcriptional gene silencing
AmiGO
<GOterm>GO:0040033</GOterm>
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