name: suppression by virus of host complement activation
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def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of complement activation. The activation of complement involves the sequential proteolysis of proteins to generate enzymes with catalytic activities. The biological functions of the complement include opsonization, inflammation, lysis of immune complexes, or enhancement of the humoral immune response. For example, the virus complement control protein (VCP) of vaccinia virus, and the complement control protein of herpesvirus inhibit C3 convertase." [PMID:21191012, PMID:7745740, UniProtKB-KW:KW-1087, VZ:811]
synonym: "inhibition of host complement activation by virus" EXACT [GOC:bf]
synonym: "inhibition of host complement cascade by virus" EXACT [GOC:bf]
synonym: "inhibition of host complement factors by virus" BROAD [UniProtKB-KW:KW-1087]
xref: .html VZ:811 "Inhibition of host complement factors by virus"
is_a: GO:0030683 ! mitigation of host immune response by virus
is_a: GO:0045916 ! negative regulation of complement activation
is_a: GO:0050794 ! regulation of cellular process
is_a: GO:0075528 ! modulation by virus of host immune response
intersection_of: GO:0019054 ! modulation by virus of host cellular process
intersection_of: negatively_regulates GO:0006956 ! complement activation
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