GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

Category:GO:0039548 ! suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity

From GONUTS
Jump to: navigation, search

DAG for GO:0039548id: GO:0039548

name: suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity
namespace: biological_process
def: "Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host IRF3 (interferon regulatory factor-3). IRF3 is a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes." [PMID:21632562]
comment: This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.
synonym: "inhibition of host IRF3 by virus" RELATED []
synonym: "inhibition of IRF3-dependent antiviral response" RELATED [PMID:19125153]
synonym: "suppression by virus of host interferon regulatory factor 3" RELATED []
synonym: "suppression by virus of host IRF3 activity" RELATED []
is_a: GO:0039537 ! suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway

AmiGO <GOterm>GO:0039548</GOterm>
Gene Ontology Home


The contents of this box are automatically generated. You can help by adding information to the "Notes"

Usage Notes

References

See Help:References for how to manage references in GONUTS.

Pages in category "GO:0039548 ! suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity"

The following 3 pages are in this category, out of 3 total.