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Category:GO:0039545 ! symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
name: symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
namespace: biological_process
def: "A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host MAVS (mitochondrial antiviral signaling protein). MAVS is a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses." [PMID:17438296, PMID:22674996]
comment: This term is for annotation of symbiont proteins that counteract the host anti-microbial innate immune response.
synonym: "inhibition of host MAVS by virus" RELATED []
synonym: "suppression by virus of host MAVS activity" RELATED []
synonym: "suppression by virus of host mitochondrial antiviral-signaling protein" RELATED []
synonym: "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity" NARROW []
xref: VZ:704
is_a: GO:0039537 ! symbiont-mediated suppression of cytoplasmic pattern recognition receptor signaling pathway
AmiGO
<GOterm>GO:0039545</GOterm>
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