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Category:GO:0038045 ! large latent transforming growth factor-beta complex
name: large latent transforming growth factor-beta complex
namespace: cellular_component
def: "A protein complex containing latency-associated proteins (LAPs), mature disulphide-linked dimeric TGF-beta, and latent TGF-beta binding proteins (LTBPs). TGF-beta is mostly secreted as part of the large latent complex, and must be subsequently released from the LLC in order to bind to cell surface receptors." [GOC:bf, PMID:2350783, PMID:8680476, PMID:9805445, Reactome:R-HSA-177107]
synonym: "large latent complex" EXACT [Reactome:R-HSA-177107]
synonym: "LLC" EXACT [Reactome:R-HSA-177107]
is_a: GO:0032991 ! protein-containing complex
AmiGO
<GOterm>GO:0038045</GOterm>
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