name: sterol regulatory element binding protein cleavage
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def: "The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids." [GOC:bf, GOC:vw, PMID:12923525]
synonym: "SREBP cleavage" EXACT 
synonym: "sterol depletion response, SREBP cleavage" EXACT 
synonym: "sterol regulatory element binding protein cleavage involved in ER-nuclear sterol response pathway" NARROW [GOC:vw]
is_a: GO:0016485 ! protein processing
is_a: GO:0044267 ! cellular protein metabolic process
relationship: part_of: GO:0032933 ! SREBP signaling pathway
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Pages in category "GO:0035103 ! sterol regulatory element binding protein cleavage"
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