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Category:GO:0032258 ! cytoplasm to vacuole transport by the Cvt pathway
name: cytoplasm to vacuole transport by the Cvt pathway
namespace: biological_process
def: "A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast." [PMID:12865942, PMID:15659643]
synonym: "cytoplasm to vacuole targeting" BROAD []
synonym: "cytoplasm-to-vacuole targeting" BROAD []
synonym: "protein localization by the Cvt pathway" EXACT []
is_a: GO:0006623 ! protein targeting to vacuole
is_a: GO:0061919 ! process utilizing autophagic mechanism
relationship: has_part: GO:0006624 ! vacuolar protein processing
AmiGO
<GOterm>GO:0032258</GOterm>
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