name: type I site-specific deoxyribonuclease activity
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def: "Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions; ATP is simultaneously hydrolyzed. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA." [PMID:15300241, PMID:15788748]
synonym: "adenosine triphosphate-dependent deoxyribonuclease activity" RELATED [EC:188.8.131.52]
synonym: "ATP-dependent DNase activity" RELATED [EC:184.108.40.206]
synonym: "deoxyribonuclease (adenosine triphosphate-hydrolyzing)" RELATED [EC:220.127.116.11]
synonym: "deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent)" RELATED [EC:18.104.22.168]
synonym: "type I restriction enzyme activity" EXACT 
synonym: "type I site-specific deoxyribonuclease activity" RELATED [EC:22.214.171.124]
is_a: GO:0015616 ! DNA translocase activity
is_a: GO:0015666 ! restriction endodeoxyribonuclease activity
is_a: GO:0016888 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters
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