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Category:GO:0008518 ! folate:monoatomic anion antiporter activity
name: folate:monoatomic anion antiporter activity
namespace: molecular_function
def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Folate derivative (out) + anion (in) = folate derivative (in) + anion (out). The Reduced Folate Carrier (RCF(SLC19A1) acts by an antiport mechanism. RCF carries several folate derivatives: MTX, PMX, ratitrexed, pralatrexate, 5-methyl THF, and 5-formyl THF." [GOC:mtg_transport, PMID:21568705, PMID:24745983, TC:2.A.48]
synonym: "folate:anion antiporter activity" BROAD []
synonym: "reduced folate carrier activity" RELATED []
synonym: "reduced folate transmembrane transporter activity" RELATED []
synonym: "reduced folate transporter" RELATED []
xref: TC:2.A.48
is_a: GO:0008509 ! monoatomic anion transmembrane transporter activity
is_a: GO:0008517 ! folic acid transmembrane transporter activity
is_a: GO:0015297 ! antiporter activity
is_a: GO:0022853 ! active monoatomic ion transmembrane transporter activity
AmiGO
<GOterm>GO:0008518</GOterm>
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Pages in category "GO:0008518 ! folate:monoatomic anion antiporter activity"
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