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Category:GO:0004410 ! homocitrate synthase activity
name: homocitrate synthase activity
namespace: molecular_function
def: "Catalysis of the reaction: 2-oxoglutarate + acetyl-CoA + H2O = CoA + H+ + homocitrate." [RHEA:12929]
comment: Note that this function was formerly EC:4.1.3.21.
synonym: "2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acetylating) activity" RELATED [EC:2.3.3.14]
synonym: "2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acetylating)" RELATED [EC:2.3.3.14]
synonym: "acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)" RELATED [EC:2.3.3.14]
synonym: "acetyl-coenzyme A:2-ketoglutarate C-acetyl transferase activity" RELATED [EC:2.3.3.14]
synonym: "homocitrate synthetase activity" RELATED [EC:2.3.3.14]
xref: EC:2.3.3.14
xref: KEGG_REACTION:R00271
xref: MetaCyc:HOMOCITRATE-SYNTHASE-RXN
xref: RHEA:12929
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer
AmiGO
<GOterm>GO:0004410</GOterm>
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