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Category:GO:0002479 ! antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
name: antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
namespace: biological_process
def: "The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules." [GOC:add, PMID:15224093, PMID:15771591, PMID:16181335]
synonym: "cross presentation" BROAD []
synonym: "cross-presentation" BROAD []
synonym: "exogenous peptide antigen processing and presentation via MHC class I, TAP-dependent" EXACT []
synonym: "TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I" EXACT []
synonym: "TAP-dependent exogenous peptide antigen processing and presentation via MHC class I" EXACT []
is_a: GO:0042590 ! antigen processing and presentation of exogenous peptide antigen via MHC class I
AmiGO
<GOterm>GO:0002479</GOterm>
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