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CORDI:DTXR

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Species (Taxon ID) Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotypegravis). (257309)
Gene Name(s) dtxR
Protein Name(s) Diphtheria toxin repressor

Iron-dependent diphtheria tox regulatory element Tox regulatory factor

External Links
UniProt P0DJL7
EMBL M34239
M80336
M80337
AY741368
AY741369
AY741370
BX248358
PIR A35968
RefSeq NP_939766.1
WP_010935052.1
PDB 1BI0
1BI1
1BI2
1BI3
1BYM
1C0W
1DDN
1DPR
1F5T
1FWZ
1G3S
1G3T
1G3W
1G3Y
1P92
1QVP
1QW1
1XCV
2DTR
2QQ9
2QQA
2QQB
2TDX
3GLX
PDBsum 1BI0
1BI1
1BI2
1BI3
1BYM
1C0W
1DDN
1DPR
1F5T
1FWZ
1G3S
1G3T
1G3W
1G3Y
1P92
1QVP
1QW1
1XCV
2DTR
2QQ9
2QQA
2QQB
2TDX
3GLX
DisProt DP00374
ProteinModelPortal P0DJL7
SMR P0DJL7
EnsemblBacteria CAE49945
GeneID 2649688
KEGG cdi:DIP1414
eggNOG COG1321
HOGENOM HOG000096101
KO K03709
OMA DSAVMAN
Proteomes UP000002198
GO GO:0005737
GO:0003677
GO:0003700
GO:0046914
GO:0006351
Gene3D 1.10.10.10
1.10.60.10
InterPro IPR007167
IPR001367
IPR022689
IPR022687
IPR008988
IPR011991
Pfam PF02742
PF01325
PF04023
SMART SM00899
SM00529
SUPFAM SSF47979
SSF50037
PROSITE PS50944

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0017124

SH3 domain binding

PMID:10339551[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:10339551[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

GO:0003700

sequence-specific DNA binding transcription factor activity

PMID:10760146[2]

ECO:0000250

F

Fig 1A

Missing: with/from

involved_in

GO:0051260

protein homooligomerization

PMID:10339551[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR022687

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR022689

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR022689

P

Seeded From UniProt

complete

enables

GO:0046914

transition metal ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001367
InterPro:IPR007167
InterPro:IPR022689
InterPro:IPR036421

F

Seeded From UniProt

complete

enables

GO:0046983

protein dimerization activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001367
InterPro:IPR036421

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Wang, G et al. (1999) Solution structure and peptide binding studies of the C-terminal src homology 3-like domain of the diphtheria toxin repressor protein. Proc. Natl. Acad. Sci. U.S.A. 96 6119-24 PubMed GONUTS page
  2. Que, Q & Helmann, JD (2000) Manganese homeostasis in Bacillus subtilis is regulated by MntR, a bifunctional regulator related to the diphtheria toxin repressor family of proteins. Mol. Microbiol. 35 1454-68 PubMed GONUTS page