GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

COFAR:XMT1

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Coffea arabica (Arabian coffee). (13443)
Gene Name(s) XMT1 (synonyms: CS1, MTL3, XRS1)
Protein Name(s) 7-methylxanthosine synthase 1

CmXRS1 Methyltransferase-like 3 CaMTL3 Xanthosine methyltransferase CaXMT1

External Links
UniProt Q9AVK0
EMBL AB048793
AB034699
AF494412
ProteinModelPortal Q9AVK0
SMR Q9AVK0
BRENDA 2.1.1.158
GO GO:0008168
GO:0009820
Gene3D 3.40.50.150
InterPro IPR005299
IPR029063
Pfam PF03492
SUPFAM SSF53335

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0008170

N-methyltransferase activity

PMID:12746542[1]

ECO:0000314

F

Based on methods: three types of cDNAs encoding N-methyltransferases were isolated from immature fruits of coffee (Coffea arabica) plants, and designated as CaXMT1, CaMXMT2, and CaDXMT1, respectively. The bacterially expressed encoded proteins were characterized for their catalytic properties. Using these recombinant proteins, catalytic specificity was determined with the following substrates: XMP, xanthosine, xanthine, 1-methylxanthine, 3-methylxanthine, 7-methylxanthine, paraxanthine, theobromine, and theophylline (Fig. ​(Fig.3B–D;3B–D; Table ​TableI).I). Purified CaXMT1 solely catalyzed conversion of xanthosine to 7-methylxanthosine

complete
CACAO 4251

enables

GO:0008168

methyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005299

F

Seeded From UniProt

complete

involved_in

GO:0009820

alkaloid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0017

P

Seeded From UniProt

complete

involved_in

GO:0032259

methylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0489

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0008168

methyltransferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0489

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Uefuji, H et al. (2003) Molecular cloning and functional characterization of three distinct N-methyltransferases involved in the caffeine biosynthetic pathway in coffee plants. Plant Physiol. 132 372-80 PubMed GONUTS page