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CHRVO:PH4H
Contents
| Species (Taxon ID) | Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 /NBRC 12614 / NCIMB 9131 / NCTC 9757). (243365) | |
| Gene Name(s) | phhA | |
| Protein Name(s) | Phenylalanine-4-hydroxylase
PAH Phe-4-monooxygenase | |
| External Links | ||
| UniProt | P30967 | |
| EMBL | M55915 AF146711 AE016825 | |
| PIR | A40996 | |
| RefSeq | NP_902850.1 WP_011136727.1 | |
| PDB | 1LTU 1LTV 1LTZ 3TCY 3TK2 3TK4 4ESM 4ETL 4JPX 4JPY | |
| PDBsum | 1LTU 1LTV 1LTZ 3TCY 3TK2 3TK4 4ESM 4ETL 4JPX 4JPY | |
| ProteinModelPortal | P30967 | |
| SMR | P30967 | |
| STRING | 243365.CV_3180 | |
| EnsemblBacteria | AAQ60846 | |
| GeneID | 2548525 | |
| KEGG | cvi:CV_3180 | |
| PATRIC | 21441114 | |
| eggNOG | COG3186 | |
| HOGENOM | HOG000253806 | |
| KO | K00500 | |
| OMA | HEVFGHC | |
| OrthoDB | EOG6W7200 | |
| BioCyc | CVIO243365:GHUD-3249-MONOMER MetaCyc:MONOMER-12067 | |
| UniPathway | UPA00139 | |
| EvolutionaryTrace | P30967 | |
| Proteomes | UP000001424 | |
| GO | GO:0005506 GO:0004505 GO:0006559 | |
| Gene3D | 1.10.800.10 | |
| InterPro | IPR001273 IPR018301 IPR019774 IPR005960 | |
| PANTHER | PTHR11473 | |
| Pfam | PF00351 | |
| PRINTS | PR00372 | |
| SUPFAM | SSF56534 | |
| TIGRFAMs | TIGR01267 | |
| PROSITE | PS00367 PS51410 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0004505 |
phenylalanine 4-monooxygenase activity |
ECO:0000314 |
F |
Fig. 1 Phenylalanine hydroxylase catalytic activity increases as DTT concentration increases. |
complete | |||||
|
enables |
GO:0004505 |
phenylalanine 4-monooxygenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004497 |
monooxygenase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004505 |
phenylalanine 4-monooxygenase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005506 |
iron ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006559 |
L-phenylalanine catabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009072 |
aromatic amino acid family metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016714 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001273 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004505 |
phenylalanine 4-monooxygenase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006559 |
L-phenylalanine catabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0585 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004497 |
monooxygenase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Panay, AJ & Fitzpatrick, PF (2008) Kinetic isotope effects on aromatic and benzylic hydroxylation by Chromobacterium violaceum phenylalanine hydroxylase as probes of chemical mechanism and reactivity. Biochemistry 47 11118-24 PubMed GONUTS page
