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CHLAE:CATL1
Contents
Species (Taxon ID) | Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops). (9534) | |
Gene Name(s) | CTSL (synonyms: CTSL1) | |
Protein Name(s) | Cathepsin L1
Cathepsin L Major excreted protein MEP Cathepsin L1 heavy chain Cathepsin L1 light chain | |
External Links | ||
UniProt | Q9GKL8 | |
EMBL | AF201700 | |
ProteinModelPortal | Q9GKL8 | |
SMR | Q9GKL8 | |
MEROPS | C01.032 | |
PRIDE | Q9GKL8 | |
HOVERGEN | HBG011513 | |
GO | GO:0005764 GO:0008234 | |
InterPro | IPR025661 IPR000169 IPR025660 IPR013128 IPR000668 IPR013201 | |
PANTHER | PTHR12411 | |
Pfam | PF08246 PF00112 | |
PRINTS | PR00705 | |
SMART | SM00848 SM00645 | |
PROSITE | PS00640 PS00139 PS00639 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0046718 |
viral entry into host cell |
ECO:0000315 |
P |
Fig. 1B and Fig. 2D CatL is not required for infection, but does enhance infection when CatB is activated. |
complete | |||||
GO:0004197 |
cysteine-type endopeptidase activity |
ECO:0000315 |
F |
Fig. 1B and Fig. 2B |
complete | |||||
GO:0046718 |
viral entry into host cell |
ECO:0000314 |
P |
Fig. 1A, 1C and Fig. 3(A,B,C) |
complete | |||||
GO:0004197 |
cysteine-type endopeptidase activity |
ECO:0000314 |
F |
Fig. 2 |
complete | |||||
part_of |
GO:0005764 |
lysosome |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0046718 |
viral entry into host cell |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0046718 |
viral entry into host cell |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0004197 |
cysteine-type endopeptidase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004197 |
cysteine-type endopeptidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006508 |
proteolysis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0008234 |
cysteine-type peptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008233 |
peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008234 |
cysteine-type peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006508 |
proteolysis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005764 |
lysosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Chandran, K et al. (2005) Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection. Science 308 1643-5 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Schornberg, K et al. (2006) Role of endosomal cathepsins in entry mediated by the Ebola virus glycoprotein. J. Virol. 80 4174-8 PubMed GONUTS page