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CHILA:DEFB1

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Species (Taxon ID) Chinchilla lanigera (Long-tailed chinchilla) (Chinchilla villidera). (34839)
Gene Name(s) DEFB1
Protein Name(s) Beta-defensin 1

BD-1 Defensin, beta 1 cBD-1

External Links
UniProt P83943
EMBL AY128668
RefSeq XP_005373890.1
ProteinModelPortal P83943
SMR P83943
GeneID 102004444
HOVERGEN HBG004834
GO GO:0005576
GO:0042742
GO:0050832
GO:0031640
InterPro IPR001855
Pfam PF00711

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0051873

killing by host of symbiont cells

PMID:14996845[1]

ECO:0000314

P

Figure 6 - bacteria and C. albicans incubated with cBD-1 show decreased survival with increased concentrations of cBD-1.

complete
CACAO 12166

part_of

GO:1990742

microvesicle

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60022

C

Seeded From UniProt

complete

part_of

GO:0019898

extrinsic component of membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60022

C

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60022

F

Seeded From UniProt

complete

part_of

GO:0097225

sperm midpiece

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60022

C

Seeded From UniProt

complete

enables

GO:0031731

CCR6 chemokine receptor binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60022

F

Seeded From UniProt

complete

involved_in

GO:0060474

positive regulation of flagellated sperm motility involved in capacitation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60022

P

Seeded From UniProt

complete

involved_in

GO:0050830

defense response to Gram-positive bacterium

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60022

P

Seeded From UniProt

complete

involved_in

GO:0050829

defense response to Gram-negative bacterium

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60022

P

Seeded From UniProt

complete

involved_in

GO:0035584

calcium-mediated signaling using intracellular calcium source

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60022

P

Seeded From UniProt

complete

involved_in

GO:0019933

cAMP-mediated signaling

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60022

P

Seeded From UniProt

complete

involved_in

GO:0050918

positive chemotaxis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0042056

P

Seeded From UniProt

complete

involved_in

GO:0060326

cell chemotaxis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q7TNV9
ensembl:ENSMUSP00000062781

P

Seeded From UniProt

complete

involved_in

GO:0042742

defense response to bacterium

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q7TNV9
ensembl:ENSMUSP00000062781

P

Seeded From UniProt

complete

enables

GO:0042056

chemoattractant activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q7TNV9
ensembl:ENSMUSP00000062781

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001855

C

Seeded From UniProt

complete

involved_in

GO:0006952

defense response

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001855

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

involved_in

GO:0006952

defense response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0211

P

Seeded From UniProt

complete

involved_in

GO:0050832

defense response to fungus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0295

P

Seeded From UniProt

complete

involved_in

GO:0042742

defense response to bacterium

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0044

P

Seeded From UniProt

complete

involved_in

GO:0031640

killing of cells of other organism

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0295

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Harris, RH et al. (2004) Identification and characterization of a mucosal antimicrobial peptide expressed by the chinchilla (Chinchilla lanigera) airway. J. Biol. Chem. 279 20250-6 PubMed GONUTS page