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CHICK:YRK

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) YRK
Protein Name(s) Proto-oncogene tyrosine-protein kinase Yrk

Yes-related kinase p60-Yrk

External Links
UniProt Q02977
EMBL X67786
PIR S33569
RefSeq NP_001103257.1
UniGene Gga.37861
ProteinModelPortal Q02977
SMR Q02977
PRIDE Q02977
GeneID 777583
KEGG gga:777583
CTD 337571
HOVERGEN HBG008761
InParanoid Q02977
KO K17511
PhylomeDB Q02977
BRENDA 2.7.10.2
NextBio 20924203
Proteomes UP000000539
GO GO:0005524
GO:0004715
GO:0045087
Gene3D 3.30.505.10
InterPro IPR028459
IPR011009
IPR000719
IPR017441
IPR001245
IPR000980
IPR001452
IPR008266
IPR020635
PANTHER PTHR24418:SF224
Pfam PF07714
PF00017
PF00018
PRINTS PR00401
PR00452
PR00109
SMART SM00252
SM00326
SM00219
SUPFAM SSF50044
SSF55550
SSF56112
PROSITE PS00107
PS50011
PS00109
PS50001
PS50002

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0038083

peptidyl-tyrosine autophosphorylation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002521528
UniProtKB:Q9H3Y6
WB:WBGene00005077

P

Seeded From UniProt

complete

part_of

GO:0031234

extrinsic component of cytoplasmic side of plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002521528
UniProtKB:P08631

C

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002521528
RGD:621423

P

Seeded From UniProt

complete

involved_in

GO:0007229

integrin-mediated signaling pathway

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95527
PANTHER:PTN001231392
UniProtKB:P09769

P

Seeded From UniProt

complete

involved_in

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002521528
UniProtKB:P07948

P

Seeded From UniProt

complete

enables

GO:0005102

signaling receptor binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0262733
PANTHER:PTN002521528
RGD:2641
RGD:620795
RGD:621017
UniProtKB:P12931

F

Seeded From UniProt

complete

enables

GO:0004715

non-membrane spanning protein tyrosine kinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95527
PANTHER:PTN002521528
UniProtKB:P09769
UniProtKB:P51451
UniProtKB:Q13882
WB:WBGene00005077

F

Seeded From UniProt

complete

involved_in

GO:0046777

protein autophosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09769
ensembl:ENSP00000363117

P

Seeded From UniProt

complete

involved_in

GO:0043552

positive regulation of phosphatidylinositol 3-kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09769
ensembl:ENSP00000363117

P

Seeded From UniProt

complete

enables

GO:0034988

Fc-gamma receptor I complex binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09769
ensembl:ENSP00000363117

F

Seeded From UniProt

complete

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09769
ensembl:ENSP00000363117

P

Seeded From UniProt

complete

part_of

GO:0016235

aggresome

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09769
ensembl:ENSP00000363117

C

Seeded From UniProt

complete

involved_in

GO:0014068

positive regulation of phosphatidylinositol 3-kinase signaling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09769
ensembl:ENSP00000363117

P

Seeded From UniProt

complete

involved_in

GO:0007229

integrin-mediated signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09769
ensembl:ENSP00000363117

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09769
ensembl:ENSP00000363117

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09769
ensembl:ENSP00000363117

C

Seeded From UniProt

complete

enables

GO:0004715

non-membrane spanning protein tyrosine kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09769
ensembl:ENSP00000363117

F

Seeded From UniProt

complete

enables

GO:0004713

protein tyrosine kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09769
ensembl:ENSP00000363117

F

Seeded From UniProt

complete

enables

GO:0001784

phosphotyrosine residue binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09769
ensembl:ENSP00000363117

F

Seeded From UniProt

complete

involved_in

GO:0050830

defense response to Gram-positive bacterium

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

P

Seeded From UniProt

complete

involved_in

GO:0050764

regulation of phagocytosis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

P

Seeded From UniProt

complete

involved_in

GO:0050715

positive regulation of cytokine secretion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

P

Seeded From UniProt

complete

involved_in

GO:0048705

skeletal system morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

P

Seeded From UniProt

complete

involved_in

GO:0045859

regulation of protein kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

P

Seeded From UniProt

complete

involved_in

GO:0045088

regulation of innate immune response

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

P

Seeded From UniProt

complete

involved_in

GO:0043306

positive regulation of mast cell degranulation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

P

Seeded From UniProt

complete

enables

GO:0034987

immunoglobulin receptor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

F

Seeded From UniProt

complete

part_of

GO:0032587

ruffle membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

C

Seeded From UniProt

complete

involved_in

GO:0030335

positive regulation of cell migration

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

P

Seeded From UniProt

complete

involved_in

GO:0030282

bone mineralization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

P

Seeded From UniProt

complete

enables

GO:0019901

protein kinase binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

F

Seeded From UniProt

complete

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

P

Seeded From UniProt

complete

part_of

GO:0015629

actin cytoskeleton

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

C

Seeded From UniProt

complete

involved_in

GO:0008360

regulation of cell shape

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

P

Seeded From UniProt

complete

involved_in

GO:0007229

integrin-mediated signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

C

Seeded From UniProt

complete

enables

GO:0004715

non-membrane spanning protein tyrosine kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

F

Seeded From UniProt

complete

enables

GO:0001784

phosphotyrosine residue binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14234
ensembl:ENSMUSP00000030693

F

Seeded From UniProt

complete

enables

GO:0004672

protein kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR008266

F

Seeded From UniProt

complete

enables

GO:0004713

protein tyrosine kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020635

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR017441

F

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR008266
InterPro:IPR020635

P

Seeded From UniProt

complete

enables

GO:0004715

non-membrane spanning protein tyrosine kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.10.2

F

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0004713

protein tyrosine kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0829

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page