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CHICK:TEN2

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) TENM2 (synonyms: ODZ2, TNM2)
Protein Name(s) Teneurin-2

Ten-2 Neurestin Protein Odd Oz/ten-m homolog 2 Tenascin-M2 Ten-m2 Teneurin transmembrane protein 2 Ten-2, soluble form Ten-2 intracellular domain Ten-2 ICD

External Links
UniProt Q9DER5
EMBL AJ279031
AJ245711
RefSeq NP_001003718.1
NP_989428.2
UniGene Gga.2983
ProteinModelPortal Q9DER5
STRING 9031.ENSGALP00000002709
PaxDb Q9DER5
PRIDE Q9DER5
GeneID 373854
KEGG gga:373854
CTD 57451
eggNOG NOG323120
HOGENOM HOG000231701
HOVERGEN HBG080306
InParanoid Q9DER5
PhylomeDB Q9DER5
NextBio 20813401
PRO PR:Q9DER5
Proteomes UP000000539
GO GO:0030054
GO:0005911
GO:0030425
GO:0043197
GO:0005783
GO:0030175
GO:0005794
GO:0030426
GO:0005887
GO:0043005
GO:0005634
GO:0005886
GO:0016605
GO:0045211
GO:0045202
GO:0050839
GO:0046982
GO:0042803
GO:0005102
GO:0007411
GO:0035584
GO:0007157
GO:0000122
GO:0051491
GO:0097264
GO:0016337
GO:0006351
Gene3D 2.120.10.30
InterPro IPR011042
IPR008969
IPR000742
IPR013032
IPR011047
IPR022385
IPR027690
IPR009471
IPR028916
IPR006530
PANTHER PTHR11219:SF8
Pfam PF06484
PF15636
SMART SM00181
SUPFAM SSF49464
SSF50998
TIGRFAMs TIGR03696
TIGR01643
PROSITE PS00022
PS01186
PS50026
PS51361

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0051491

positive regulation of filopodium assembly

PMID:10588872[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0050839

cell adhesion molecule binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9NT68-2

F

Seeded From UniProt

complete

enables

GO:0050839

cell adhesion molecule binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9R1K2

F

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9WTS5

F

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9R1K2

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9R1K2

C

Seeded From UniProt

complete

part_of

GO:0043197

dendritic spine

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9R1K2

C

Seeded From UniProt

complete

part_of

GO:0043005

neuron projection

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9R1K2

C

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9WTS5

F

Seeded From UniProt

complete

involved_in

GO:0035584

calcium-mediated signaling using intracellular calcium source

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9NT68-2

P

Seeded From UniProt

complete

part_of

GO:0030426

growth cone

PMID:12361962[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0030425

dendrite

PMID:12361962[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0030175

filopodium

PMID:12361962[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

PMID:12361962[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016605

PML body

PMID:12783990[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0098609

cell-cell adhesion

PMID:12361962[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007411

axon guidance

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9NT68-2

P

Seeded From UniProt

complete

involved_in

GO:0007157

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9NT68-2

P

Seeded From UniProt

complete

involved_in

GO:0007157

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9R1K2

P

Seeded From UniProt

complete

part_of

GO:0005911

cell-cell junction

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9NT68-2

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:10588872[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:12783990[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

PMID:10588872[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

PMID:10588872[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:12783990[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005102

signaling receptor binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9NT68-2

F

Seeded From UniProt

complete

enables

GO:0005102

signaling receptor binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9R1K2

F

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

PMID:12783990[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0050839

cell adhesion molecule binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000131466
RGD:727907
UniProtKB:Q9NT68

F

Seeded From UniProt

complete

involved_in

GO:0048666

neuron development

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000131466
UniProtKB:Q6N022

P

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1345183
MGI:MGI:1345184
MGI:MGI:1345185
PANTHER:PTN000131466

F

Seeded From UniProt

complete

part_of

GO:0043005

neuron projection

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2447063
PANTHER:PTN000131466
RGD:727907

C

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1345183
MGI:MGI:1345184
MGI:MGI:1345185
MGI:MGI:2447063
PANTHER:PTN000131466

F

Seeded From UniProt

complete

involved_in

GO:0007157

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000131466
RGD:727907
UniProtKB:Q9NT68

P

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001881

F

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027689

C

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009471

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009471

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256
UniProtKB-SubCell:SL-0095

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770
UniProtKB-SubCell:SL-0258

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0130

P

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333
UniProtKB-SubCell:SL-0132

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0628
UniProtKB-SubCell:SL-0219

C

Seeded From UniProt

complete

part_of

GO:0043005

neuron projection

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0771
UniProtKB-SubCell:SL-0261

C

Seeded From UniProt

complete

part_of

GO:0030175

filopodium

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0286

C

Seeded From UniProt

complete

part_of

GO:0030426

growth cone

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0288

C

Seeded From UniProt

complete

part_of

GO:0016605

PML body

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0465

C

Seeded From UniProt

complete

part_of

GO:0030425

dendrite

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0283

C

Seeded From UniProt

complete

part_of

GO:0043197

dendritic spine

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0284

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Rubin, BP et al. (1999) Teneurins: a novel family of neuronal cell surface proteins in vertebrates, homologous to the Drosophila pair-rule gene product Ten-m. Dev. Biol. 216 195-209 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Rubin, BP et al. (2002) Teneurin 2 is expressed by the neurons of the thalamofugal visual system in situ and promotes homophilic cell-cell adhesion in vitro. Development 129 4697-705 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Bagutti, C et al. (2003) The intracellular domain of teneurin-2 has a nuclear function and represses zic-1-mediated transcription. J. Cell. Sci. 116 2957-66 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page