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CHICK:SOX21
Contents
| Species (Taxon ID) | Gallus gallus (Chicken). (9031) | |
| Gene Name(s) | SOX21 | |
| Protein Name(s) | Transcription factor SOX-21 | |
| External Links | ||
| UniProt | Q9W7R5 | |
| EMBL | AB026623 | |
| ProteinModelPortal | Q9W7R5 | |
| SMR | Q9W7R5 | |
| HOVERGEN | HBG105618 | |
| InParanoid | Q9W7R5 | |
| PhylomeDB | Q9W7R5 | |
| Proteomes | UP000000539 | |
| GO | GO:0005634 GO:0043565 GO:0000122 GO:0045892 GO:0006351 | |
| Gene3D | 1.10.30.10 | |
| InterPro | IPR009071 IPR022097 | |
| Pfam | PF00505 PF12336 | |
| SMART | SM00398 | |
| SUPFAM | SSF47095 | |
| PROSITE | PS50118 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0048839 |
inner ear development |
ECO:0000315 |
P |
Figure 4 shows that sox21 promotes hair cell formation in vestibular patches during late embryonic stages. In vestibular patches, the majority of pTRE-eGFP transfected cells had support cell rather than hair cell morphologies. However, the majority of cells transfected with pTRE-eGFP-Sox21 had hair cell morphology. |
complete | |||||
|
involved_in |
GO:0045595 |
regulation of cell differentiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
occurs_in:(CL:0002374) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042472 |
inner ear morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
occurs_in:(CL:0002374) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0048839 |
inner ear development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045892 |
negative regulation of transcription, DNA-templated |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000305 |
curator inference used in manual assertion |
GO:0043565 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000122 |
negative regulation of transcription by RNA polymerase II |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2654070 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0044798 |
nuclear transcription factor complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:103559 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030182 |
neuron differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000030745 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98363 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007417 |
central nervous system development |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000030745 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:103559 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000411 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:103559 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000122 |
negative regulation of transcription by RNA polymerase II |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98363 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q811W0 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043588 |
skin development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q811W0 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q811W0 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q811W0 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q811W0 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0001228 |
DNA-binding transcription activator activity, RNA polymerase II-specific |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q811W0 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000978 |
RNA polymerase II proximal promoter sequence-specific DNA binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q811W0 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0048863 |
stem cell differentiation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9Y651 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Freeman, SD & Daudet, N (2012) Artificial induction of Sox21 regulates sensory cell formation in the embryonic chicken inner ear. PLoS ONE 7 e46387 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Uchikawa, M et al. (1999) Two distinct subgroups of Group B Sox genes for transcriptional activators and repressors: their expression during embryonic organogenesis of the chicken. Mech. Dev. 84 103-20 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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