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CHICK:IL6

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) IL6
Protein Name(s) Interleukin-6

ChIL-6 IL-6

External Links
UniProt Q90YI0
EMBL AJ250838
AJ309540
RefSeq NP_989959.1
UniGene Gga.2769
ProteinModelPortal Q90YI0
PaxDb Q90YI0
Ensembl ENSGALT00000017759
GeneID 395337
KEGG gga:395337
CTD 3569
eggNOG NOG48083
GeneTree ENSGT00390000000878
HOGENOM HOG000208208
InParanoid Q90YI0
KO K05405
OMA CENSMEM
PhylomeDB Q90YI0
Reactome REACT_197119
REACT_214700
REACT_260156
NextBio 20815422
PRO PR:Q90YI0
Proteomes UP000000539
GO GO:0009897
GO:0005615
GO:0005896
GO:0005125
GO:0006953
GO:0060445
GO:0070301
GO:0071222
GO:0050829
GO:0050830
GO:0042832
GO:0051607
GO:0031018
GO:0060664
GO:0070091
GO:0070102
GO:0046716
GO:0043066
GO:0045079
GO:0032966
GO:0046888
GO:0031175
GO:0001781
GO:0002675
GO:0043065
GO:0050871
GO:0032722
GO:0050679
GO:0051024
GO:0032755
GO:0043410
GO:0033138
GO:0051091
GO:0048661
GO:0042102
GO:0045630
GO:0045944
GO:0045727
GO:0042517
GO:0010574
GO:0051384
GO:0032494
GO:0009611
GO:0072540
Gene3D 1.20.1250.10
InterPro IPR009079
IPR012351
IPR003574
IPR003573
PANTHER PTHR11457
Pfam PF00489
PRINTS PR00433
PR00434
SMART SM00126
SUPFAM SSF47266
PROSITE PS00254

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0070417

cellular response to cold

PMID:16150487[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

PMID:19776194[2]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030474

F

Seeded From UniProt

complete

enables

GO:0005138

interleukin-6 receptor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003574

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003574
InterPro:IPR030474

C

Seeded From UniProt

complete

involved_in

GO:0006955

immune response

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003574
InterPro:IPR030474

P

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0339

F

Seeded From UniProt

complete

involved_in

GO:0006953

acute-phase response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0011

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0202

F

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0202

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Hangalapura, BN et al. (2006) Cold stress equally enhances in vivo pro-inflammatory cytokine gene expression in chicken lines divergently selected for antibody responses. Dev. Comp. Immunol. 30 503-11 PubMed GONUTS page
  2. Lu, Y et al. (2009) Expression profiles of genes in Toll-like receptor-mediated signaling of broilers infected with Clostridium perfringens. Clin. Vaccine Immunol. 16 1639-47 PubMed GONUTS page