CHICK:Q3C2H7

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	Six2 (ECO:0000313 with EMBL:BAE46750.1)
Protein Name(s)	Sine oculis-related homeobox 2 homolog (ECO:0000313 with EMBL:BAE46750.1)
External Links
UniProt	Q3C2H7
EMBL	AB199732
RefSeq	NP_001038160.1
UniGene	Gga.23686
ProteinModelPortal	Q3C2H7
GeneID	724086
KEGG	gga:724086
CTD	10736
HOVERGEN	HBG003609
PhylomeDB	Q3C2H7
NextBio	20902648
PRO	PR:Q3C2H7
ExpressionAtlas	Q3C2H7
GO	GO:0005634 GO:0043565 GO:0003700 GO:0008283 GO:0002062 GO:0048701 GO:0003337 GO:0007501 GO:0042474 GO:0045596 GO:0045944 GO:0006606
Gene3D	1.10.10.60
InterPro	IPR017970 IPR001356 IPR009057
Pfam	PF00046
SMART	SM00389
SUPFAM	SSF46689
PROSITE	PS00027 PS50071

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:1902732	positive regulation of chondrocyte proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0097168	mesenchymal stem cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0090189	regulation of branching involved in ureteric bud morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0072161	mesenchymal cell differentiation involved in kidney development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0072137	condensed mesenchymal cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0072038	mesenchymal stem cell maintenance involved in nephron morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0072028	nephron morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0072006	nephron development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0048704	embryonic skeletal system morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0048701	embryonic cranial skeleton morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0048557	embryonic digestive tract morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0045596	negative regulation of cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
enables	GO:0044877	protein-containing complex binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	F		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	F		Seeded From UniProt	complete
involved_in	GO:0042474	middle ear morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0032330	regulation of chondrocyte differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0030278	regulation of ossification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0009948	anterior/posterior axis specification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0008283	cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	F		Seeded From UniProt	complete
involved_in	GO:0007501	mesodermal cell fate specification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0006606	protein import into nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	F		Seeded From UniProt	complete
involved_in	GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0002062	chondrocyte differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0001822	kidney development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
involved_in	GO:0001656	metanephros development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	P		Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	F		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q62232 ensembl:ENSMUSP00000125871	F		Seeded From UniProt	complete
involved_in	GO:0016477	cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NPC8 ensembl:ENSP00000304502	P		Seeded From UniProt	complete
involved_in	GO:0008283	cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NPC8 ensembl:ENSP00000304502	P		Seeded From UniProt	complete
involved_in	GO:0001822	kidney development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NPC8 ensembl:ENSP00000304502	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001356 InterPro:IPR009057	F		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017970	P		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017970	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0371	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0539	C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000401037	C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000401037	F		Seeded From UniProt	complete
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References

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