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CHICK:PTHY

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) PTH
Protein Name(s) Parathyroid hormone

PTH

External Links
UniProt P15743
EMBL M31604
M36522
PIR A34937
RefSeq NP_990783.1
UniGene Gga.78
ProteinModelPortal P15743
SMR P15743
PaxDb P15743
Ensembl ENSGALT00000008593
GeneID 396436
KEGG gga:396436
CTD 5741
eggNOG NOG41709
GeneTree ENSGT00390000018603
HOGENOM HOG000033707
HOVERGEN HBG008319
InParanoid P15743
KO K05261
OMA HNLGEHR
OrthoDB EOG7ZGX5Q
PhylomeDB P15743
TreeFam TF336197
Reactome REACT_245585
REACT_246971
NextBio 20816477
PRO PR:P15743
Proteomes UP000000539
GO GO:0005615
GO:0003705
GO:0006874
GO:0000122
GO:0030501
GO:0030819
GO:0046326
GO:0045725
GO:0009967
GO:0045944
InterPro IPR003625
IPR001415
PANTHER PTHR10541
Pfam PF01279
PIRSF PIRSF001832
SMART SM00087
PROSITE PS00335

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0031856

parathyroid hormone receptor binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000057163
RGD:3440

F

Seeded From UniProt

complete

involved_in

GO:0007267

cell-cell signaling

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000057163
RGD:3440

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97799
PANTHER:PTN000057163
RGD:3440

C

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97799
PANTHER:PTN000057163
RGD:3440
UniProtKB:P01270

F

Seeded From UniProt

complete

part_of

GO:0005623

cell

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0006874

C

Seeded From UniProt

complete

part_of

GO:0005623

cell

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0006874

C

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

involved_in

GO:0060732

positive regulation of inositol phosphate biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

P

Seeded From UniProt

complete

enables

GO:0051428

peptide hormone receptor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

F

Seeded From UniProt

complete

enables

GO:0048018

receptor ligand activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

F

Seeded From UniProt

complete

enables

GO:0047485

protein N-terminus binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

F

Seeded From UniProt

complete

involved_in

GO:0046326

positive regulation of glucose import

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

P

Seeded From UniProt

complete

involved_in

GO:0045725

positive regulation of glycogen biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

P

Seeded From UniProt

complete

involved_in

GO:0034645

cellular macromolecule biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

P

Seeded From UniProt

complete

enables

GO:0031857

type 1 parathyroid hormone receptor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

F

Seeded From UniProt

complete

involved_in

GO:0030501

positive regulation of bone mineralization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

P

Seeded From UniProt

complete

involved_in

GO:0010468

regulation of gene expression

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

P

Seeded From UniProt

complete

involved_in

GO:0007202

activation of phospholipase C activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

P

Seeded From UniProt

complete

involved_in

GO:0007189

adenylate cyclase-activating G protein-coupled receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

P

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

F

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

F

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01270
ensembl:ENSP00000282091

P

Seeded From UniProt

complete

involved_in

GO:0090290

positive regulation of osteoclast proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

P

Seeded From UniProt

complete

involved_in

GO:0071866

negative regulation of apoptotic process in bone marrow cell

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

P

Seeded From UniProt

complete

involved_in

GO:0071864

positive regulation of cell proliferation in bone marrow

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

P

Seeded From UniProt

complete

involved_in

GO:0055074

calcium ion homeostasis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

P

Seeded From UniProt

complete

involved_in

GO:0055062

phosphate ion homeostasis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

P

Seeded From UniProt

complete

involved_in

GO:0048873

homeostasis of number of cells within a tissue

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

P

Seeded From UniProt

complete

involved_in

GO:0030282

bone mineralization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

P

Seeded From UniProt

complete

involved_in

GO:0010960

magnesium ion homeostasis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

P

Seeded From UniProt

complete

involved_in

GO:0010468

regulation of gene expression

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

P

Seeded From UniProt

complete

involved_in

GO:0009967

positive regulation of signal transduction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

P

Seeded From UniProt

complete

involved_in

GO:0007189

adenylate cyclase-activating G protein-coupled receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

P

Seeded From UniProt

complete

involved_in

GO:0006874

cellular calcium ion homeostasis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

P

Seeded From UniProt

complete

involved_in

GO:0006816

calcium ion transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

C

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0L6
ensembl:ENSMUSP00000078723

F

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001415
InterPro:IPR003625

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001415
InterPro:IPR003625

C

Seeded From UniProt

complete

involved_in

GO:0006874

cellular calcium ion homeostasis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003625

P

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0372

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page