CHICK:PTHY

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	PTH
Protein Name(s)	Parathyroid hormone PTH
External Links
UniProt	P15743
EMBL	M31604 M36522
PIR	A34937
RefSeq	NP_990783.1
UniGene	Gga.78
ProteinModelPortal	P15743
SMR	P15743
PaxDb	P15743
Ensembl	ENSGALT00000008593
GeneID	396436
KEGG	gga:396436
CTD	5741
eggNOG	NOG41709
GeneTree	ENSGT00390000018603
HOGENOM	HOG000033707
HOVERGEN	HBG008319
InParanoid	P15743
KO	K05261
OMA	HNLGEHR
OrthoDB	EOG7ZGX5Q
PhylomeDB	P15743
TreeFam	TF336197
Reactome	REACT_245585 REACT_246971
NextBio	20816477
PRO	PR:P15743
Proteomes	UP000000539
GO	GO:0005615 GO:0003705 GO:0006874 GO:0000122 GO:0030501 GO:0030819 GO:0046326 GO:0045725 GO:0009967 GO:0045944
InterPro	IPR003625 IPR001415
PANTHER	PTHR10541
Pfam	PF01279
PIRSF	PIRSF001832
SMART	SM00087
PROSITE	PS00335

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0031856	parathyroid hormone receptor binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000057163 RGD:3440	F	Seeded From UniProt	complete
involved_in	GO:0007267	cell-cell signaling	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000057163 RGD:3440	P	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97799 PANTHER:PTN000057163 RGD:3440	C	Seeded From UniProt	complete
enables	GO:0005179	hormone activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97799 PANTHER:PTN000057163 RGD:3440 UniProtKB:P01270	F	Seeded From UniProt	complete
part_of	GO:0005623	cell	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0006874	C	Seeded From UniProt	complete
part_of	GO:0005623	cell	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0006874	C	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005179	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005179	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005179	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005179	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005179	P	Seeded From UniProt	complete
involved_in	GO:0060732	positive regulation of inositol phosphate biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	P	Seeded From UniProt	complete
enables	GO:0051428	peptide hormone receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	F	Seeded From UniProt	complete
enables	GO:0048018	receptor ligand activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	F	Seeded From UniProt	complete
enables	GO:0047485	protein N-terminus binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	F	Seeded From UniProt	complete
involved_in	GO:0046326	positive regulation of glucose import	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	P	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	P	Seeded From UniProt	complete
involved_in	GO:0045725	positive regulation of glycogen biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	P	Seeded From UniProt	complete
involved_in	GO:0034645	cellular macromolecule biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	P	Seeded From UniProt	complete
enables	GO:0031857	type 1 parathyroid hormone receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	F	Seeded From UniProt	complete
involved_in	GO:0030501	positive regulation of bone mineralization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	P	Seeded From UniProt	complete
involved_in	GO:0010468	regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	P	Seeded From UniProt	complete
involved_in	GO:0007202	activation of phospholipase C activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	P	Seeded From UniProt	complete
involved_in	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	P	Seeded From UniProt	complete
enables	GO:0005179	hormone activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	F	Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	F	Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01270 ensembl:ENSP00000282091	P	Seeded From UniProt	complete
involved_in	GO:0090290	positive regulation of osteoclast proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	P	Seeded From UniProt	complete
involved_in	GO:0071866	negative regulation of apoptotic process in bone marrow cell	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	P	Seeded From UniProt	complete
involved_in	GO:0071864	positive regulation of cell proliferation in bone marrow	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	P	Seeded From UniProt	complete
involved_in	GO:0055074	calcium ion homeostasis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	P	Seeded From UniProt	complete
involved_in	GO:0055062	phosphate ion homeostasis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	P	Seeded From UniProt	complete
involved_in	GO:0048873	homeostasis of number of cells within a tissue	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	P	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	P	Seeded From UniProt	complete
involved_in	GO:0030282	bone mineralization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	P	Seeded From UniProt	complete
involved_in	GO:0010960	magnesium ion homeostasis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	P	Seeded From UniProt	complete
involved_in	GO:0010468	regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	P	Seeded From UniProt	complete
involved_in	GO:0009967	positive regulation of signal transduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	P	Seeded From UniProt	complete
involved_in	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	P	Seeded From UniProt	complete
involved_in	GO:0006874	cellular calcium ion homeostasis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	P	Seeded From UniProt	complete
involved_in	GO:0006816	calcium ion transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	P	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	C	Seeded From UniProt	complete
enables	GO:0005179	hormone activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0L6 ensembl:ENSMUSP00000078723	F	Seeded From UniProt	complete
enables	GO:0005179	hormone activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001415 InterPro:IPR003625	F	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001415 InterPro:IPR003625	C	Seeded From UniProt	complete
involved_in	GO:0006874	cellular calcium ion homeostasis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003625	P	Seeded From UniProt	complete
enables	GO:0005179	hormone activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0372	F	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:PTHY

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