CHICK:PRIO

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	PRNP (synonyms: PRN-P)
Protein Name(s)	Major prion protein homolog 65-21 protein Acetylcholine receptor-inducing activity ARIA PR-LP
External Links
UniProt	P27177
EMBL	M95404 M61145
PIR	A37372 A41280 A46280
RefSeq	NP_990796.2
UniGene	Gga.3867
PDB	1U3M
PDBsum	1U3M
ProteinModelPortal	P27177
SMR	P27177
STRING	9031.ENSGALP00000040285
PaxDb	P27177
PRIDE	P27177
Ensembl	ENSGALT00000000277
GeneID	396452
KEGG	gga:396452
CTD	5621
eggNOG	NOG41716
GeneTree	ENSGT00510000049083
HOGENOM	HOG000232077
HOVERGEN	HBG008260
InParanoid	P27177
KO	K05634
OMA	QVYYRPV
OrthoDB	EOG7DRJ4Q
PhylomeDB	P27177
TreeFam	TF105188
Reactome	REACT_230524
EvolutionaryTrace	P27177
NextBio	20816493
PRO	PR:P27177
Proteomes	UP000000539
GO	GO:0031225 GO:0005783 GO:0070062 GO:0005794 GO:0045121 GO:0005886 GO:0005507 GO:0046007 GO:0043066 GO:0070885 GO:0032689 GO:0032700 GO:0032703 GO:0001933 GO:0043433 GO:0050860 GO:0051260 GO:1901379 GO:0032880 GO:0006979
Gene3D	1.10.790.10
InterPro	IPR000817 IPR022416 IPR025860
PANTHER	PTHR11522
Pfam	PF00377 PF11587
SMART	SM00157
SUPFAM	SSF54098
PROSITE	PS00291 PS00706

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0098737	protein insertion into plasma membrane	PMID:7679512^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0002372)	Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	PMID:7679512^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0002372)	Seeded From UniProt	complete
involved_in	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	PMID:7679512^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0002372)	Seeded From UniProt	complete
part_of	GO:0005623	cell	PMID:8386755^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000955)	Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	PMID:8386755^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	happens_during:(GO:0007528)	Seeded From UniProt	complete
involved_in	GO:0010870	positive regulation of receptor biosynthetic process	PMID:8386755^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0000056)	Seeded From UniProt	complete
involved_in	GO:0098737	protein insertion into plasma membrane	PMID:8386755^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0000056)	Seeded From UniProt	complete
part_of	GO:0005604	basement membrane	PMID:7559763^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001029) part_of:(UBERON:0001112)	Seeded From UniProt	complete
part_of	GO:0043083	synaptic cleft	PMID:7559763^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001029) part_of:(UBERON:0001112)	Seeded From UniProt	complete
enables	GO:0005507	copper ion binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P04156	F		Seeded From UniProt	complete
involved_in	GO:1904646	cellular response to amyloid-beta	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591 UniProtKB:P04156	P		Seeded From UniProt	complete
enables	GO:1903136	cuprous ion binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000162591 UniProtKB:P04156	F		Seeded From UniProt	complete
enables	GO:1903135	cupric ion binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591	F		Seeded From UniProt	complete
involved_in	GO:1903078	positive regulation of protein localization to plasma membrane	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591 RGD:3410	P		Seeded From UniProt	complete
involved_in	GO:1902430	negative regulation of amyloid-beta formation	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591	P		Seeded From UniProt	complete
involved_in	GO:1901216	positive regulation of neuron death	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591 UniProtKB:P04156	P		Seeded From UniProt	complete
involved_in	GO:1900449	regulation of glutamate receptor signaling pathway	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591	P		Seeded From UniProt	complete
involved_in	GO:0061098	positive regulation of protein tyrosine kinase activity	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000162591 UniProtKB:P04156	P		Seeded From UniProt	complete
involved_in	GO:0051260	protein homooligomerization	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000162591 UniProtKB:P04156	P		Seeded From UniProt	complete
enables	GO:0051087	chaperone binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000162591 RGD:3410	F		Seeded From UniProt	complete
involved_in	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591 UniProtKB:P04156 UniProtKB:P27177	P		Seeded From UniProt	complete
involved_in	GO:0046686	response to cadmium ion	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000162591 RGD:3410	P		Seeded From UniProt	complete
enables	GO:0044877	protein-containing complex binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591 UniProtKB:P04156	F		Seeded From UniProt	complete
enables	GO:0044325	ion channel binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000162591 RGD:3410	F		Seeded From UniProt	complete
involved_in	GO:0043086	negative regulation of catalytic activity	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000162591 RGD:3410	P		Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591 RGD:3410	P		Seeded From UniProt	complete
enables	GO:0043008	ATP-dependent protein binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000162591 RGD:3410	F		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591 UniProtKB:P04156	F		Seeded From UniProt	complete
enables	GO:0038023	signaling receptor activity	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591	F		Seeded From UniProt	complete
involved_in	GO:0035584	calcium-mediated signaling using intracellular calcium source	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591 UniProtKB:P04156	P		Seeded From UniProt	complete
involved_in	GO:0032147	activation of protein kinase activity	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591	P		Seeded From UniProt	complete
enables	GO:0031802	type 5 metabotropic glutamate receptor binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591 RGD:3410 UniProtKB:P04156	F		Seeded From UniProt	complete
enables	GO:0008017	microtubule binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000162591 UniProtKB:P04156	F		Seeded From UniProt	complete
involved_in	GO:0007611	learning or memory	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591 RGD:3410	P		Seeded From UniProt	complete
involved_in	GO:0006979	response to oxidative stress	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN002574842 RGD:3410 UniProtKB:P04156 UniProtKB:P09525	C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574842 UniProtKB:P04156 UniProtKB:P13214	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN002574842 RGD:3410 UniProtKB:P04156 UniProtKB:P09525 UniProtKB:P13214	C		Seeded From UniProt	complete
enables	GO:0005539	glycosaminoglycan binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591	F		Seeded From UniProt	complete
enables	GO:0005521	lamin binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000162591 RGD:3410	F		Seeded From UniProt	complete
enables	GO:0002020	protease binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591	F		Seeded From UniProt	complete
enables	GO:0001540	amyloid-beta binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97769 PANTHER:PTN000162591 UniProtKB:P04156	F		Seeded From UniProt	complete
involved_in	GO:1904646	cellular response to amyloid-beta	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	P		Seeded From UniProt	complete
enables	GO:1903136	cuprous ion binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	F		Seeded From UniProt	complete
involved_in	GO:1902938	regulation of intracellular calcium activated chloride channel activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	P		Seeded From UniProt	complete
involved_in	GO:0071280	cellular response to copper ion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	P		Seeded From UniProt	complete
involved_in	GO:0061098	positive regulation of protein tyrosine kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	P		Seeded From UniProt	complete
involved_in	GO:0051260	protein homooligomerization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	P		Seeded From UniProt	complete
involved_in	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	P		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	C		Seeded From UniProt	complete
enables	GO:0044877	protein-containing complex binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	F		Seeded From UniProt	complete
involved_in	GO:0043525	positive regulation of neuron apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	P		Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	C		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	F		Seeded From UniProt	complete
involved_in	GO:0035584	calcium-mediated signaling using intracellular calcium source	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	P		Seeded From UniProt	complete
part_of	GO:0031965	nuclear membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	C		Seeded From UniProt	complete
enables	GO:0031802	type 5 metabotropic glutamate receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	F		Seeded From UniProt	complete
involved_in	GO:0031648	protein destabilization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	P		Seeded From UniProt	complete
part_of	GO:0030425	dendrite	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	C		Seeded From UniProt	complete
part_of	GO:0016234	inclusion body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	C		Seeded From UniProt	complete
enables	GO:0015631	tubulin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	F		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	C		Seeded From UniProt	complete
enables	GO:0008017	microtubule binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	C		Seeded From UniProt	complete
enables	GO:0005507	copper ion binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	F		Seeded From UniProt	complete
enables	GO:0001540	amyloid-beta binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04156 ensembl:ENSP00000368752	F		Seeded From UniProt	complete
involved_in	GO:1990535	neuron projection maintenance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:1905664	regulation of calcium ion import across plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:1904646	cellular response to amyloid-beta	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:1904645	response to amyloid-beta	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
enables	GO:1903135	cupric ion binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	F		Seeded From UniProt	complete
involved_in	GO:1903078	positive regulation of protein localization to plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:1902992	negative regulation of amyloid precursor protein catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:1902951	negative regulation of dendritic spine maintenance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:1902430	negative regulation of amyloid-beta formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:1901379	regulation of potassium ion transmembrane transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:1901216	positive regulation of neuron death	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:1900449	regulation of glutamate receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:0090647	modulation of age-related behavioral decline	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:0090314	positive regulation of protein targeting to membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:0050860	negative regulation of T cell receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:0046007	negative regulation of activated T cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	C		Seeded From UniProt	complete
enables	GO:0044877	protein-containing complex binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	F		Seeded From UniProt	complete
involved_in	GO:0043433	negative regulation of DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	F		Seeded From UniProt	complete
enables	GO:0038023	signaling receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	F		Seeded From UniProt	complete
involved_in	GO:0035690	cellular response to drug	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:0035584	calcium-mediated signaling using intracellular calcium source	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:0032880	regulation of protein localization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:0032703	negative regulation of interleukin-2 production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:0032700	negative regulation of interleukin-17 production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:0032689	negative regulation of interferon-gamma production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:0032147	activation of protein kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
enables	GO:0031802	type 5 metabotropic glutamate receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	F		Seeded From UniProt	complete
part_of	GO:0030425	dendrite	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	C		Seeded From UniProt	complete
involved_in	GO:0010942	positive regulation of cell death	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	C		Seeded From UniProt	complete
involved_in	GO:0007611	learning or memory	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
involved_in	GO:0006979	response to oxidative stress	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	C		Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	C		Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	C		Seeded From UniProt	complete
enables	GO:0005539	glycosaminoglycan binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	F		Seeded From UniProt	complete
enables	GO:0005507	copper ion binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	F		Seeded From UniProt	complete
enables	GO:0002020	protease binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	F		Seeded From UniProt	complete
involved_in	GO:0001933	negative regulation of protein phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	P		Seeded From UniProt	complete
enables	GO:0001540	amyloid-beta binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04925 ensembl:ENSMUSP00000088833	F		Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q53YK7 ensembl:ENSP00000368752	C		Seeded From UniProt	complete
part_of	GO:0031965	nuclear membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q53YK7 ensembl:ENSP00000368752	C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q53YK7 ensembl:ENSP00000368752	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000817 InterPro:IPR022416 InterPro:IPR036924	C		Seeded From UniProt	complete
involved_in	GO:0051260	protein homooligomerization	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000817 InterPro:IPR022416 InterPro:IPR036924	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
part_of	GO:0031225	anchored component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0336	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Corfas, G et al. (1993) ARIA, a protein that stimulates acetylcholine receptor synthesis, also induces tyrosine phosphorylation of a 185-kDa muscle transmembrane protein. Proc. Natl. Acad. Sci. U.S.A. 90 1624-8 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Corfas, G & Fischbach, GD (1993) The number of Na+ channels in cultured chick muscle is increased by ARIA, an acetylcholine receptor-inducing activity. J. Neurosci. 13 2118-25 PubMed GONUTS page
↑ ^3.0 ^3.1 Goodearl, AD et al. (1995) ARIA is concentrated in the synaptic basal lamina of the developing chick neuromuscular junction. J. Cell Biol. 130 1423-34 PubMed GONUTS page
↑ ^4.00 ^4.01 ^4.02 ^4.03 ^4.04 ^4.05 ^4.06 ^4.07 ^4.08 ^4.09 ^4.10 ^4.11 ^4.12 ^4.13 ^4.14 ^4.15 ^4.16 ^4.17 ^4.18 ^4.19 ^4.20 ^4.21 ^4.22 ^4.23 ^4.24 ^4.25 ^4.26 ^4.27 ^4.28 ^4.29 ^4.30 ^4.31 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:7679512-1] 1.0 ^1.1 ^1.2 Corfas, G et al. (1993) ARIA, a protein that stimulates acetylcholine receptor synthesis, also induces tyrosine phosphorylation of a 185-kDa muscle transmembrane protein. Proc. Natl. Acad. Sci. U.S.A. 90 1624-8 PubMed GONUTS page

[PMID:8386755-2] 2.0 ^2.1 ^2.2 ^2.3 Corfas, G & Fischbach, GD (1993) The number of Na+ channels in cultured chick muscle is increased by ARIA, an acetylcholine receptor-inducing activity. J. Neurosci. 13 2118-25 PubMed GONUTS page

[PMID:7559763-3] 3.0 ^3.1 Goodearl, AD et al. (1995) ARIA is concentrated in the synaptic basal lamina of the developing chick neuromuscular junction. J. Cell Biol. 130 1423-34 PubMed GONUTS page

[PMID:21873635-4] 4.00 ^4.01 ^4.02 ^4.03 ^4.04 ^4.05 ^4.06 ^4.07 ^4.08 ^4.09 ^4.10 ^4.11 ^4.12 ^4.13 ^4.14 ^4.15 ^4.16 ^4.17 ^4.18 ^4.19 ^4.20 ^4.21 ^4.22 ^4.23 ^4.24 ^4.25 ^4.26 ^4.27 ^4.28 ^4.29 ^4.30 ^4.31 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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