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CHICK:PDGFC

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) PDGFC (synonyms: SCDGF)
Protein Name(s) Platelet-derived growth factor C

PDGF-C Spinal cord-derived growth factor Platelet-derived growth factor C, latent form PDGFC latent form Platelet-derived growth factor C, receptor-binding form PDGFC receptor-binding form

External Links
UniProt Q9I946
EMBL AB033829
RefSeq NP_990052.1
UniGene Gga.1907
ProteinModelPortal Q9I946
STRING 9031.ENSGALP00000015259
PaxDb Q9I946
Ensembl ENSGALT00000015275
GeneID 395469
KEGG gga:395469
CTD 56034
eggNOG NOG74970
GeneTree ENSGT00390000005171
HOGENOM HOG000261610
HOVERGEN HBG057324
InParanoid Q9I946
KO K05450
OMA DCVCRGN
OrthoDB EOG7VB2FN
PhylomeDB Q9I946
TreeFam TF332130
Reactome REACT_258033
NextBio 20815550
PRO PR:Q9I946
Proteomes UP000000539
GO GO:0009986
GO:0005737
GO:0005615
GO:0070062
GO:0005886
GO:0007171
GO:0071230
GO:0009887
GO:0048008
GO:0051781
GO:0045740
GO:0048146
GO:0050730
Gene3D 2.10.90.10
2.60.120.290
InterPro IPR000859
IPR029034
IPR029817
IPR000072
PANTHER PTHR10127:SF570
Pfam PF00431
PF00341
SMART SM00042
SM00141
SUPFAM SSF49854
SSF57501
PROSITE PS01180
PS50278

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0070374

positive regulation of ERK1 and ERK2 cascade

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000180420
UniProtKB:P01127
UniProtKB:P04085

P

Seeded From UniProt

complete

involved_in

GO:0048008

platelet-derived growth factor receptor signaling pathway

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1859631
PANTHER:PTN000180420
RGD:3283
UniProtKB:P01127
UniProtKB:P04085
UniProtKB:Q9NRA1

P

Seeded From UniProt

complete

involved_in

GO:0043406

positive regulation of MAP kinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000180420
RGD:3283
UniProtKB:P01127
UniProtKB:P04085

P

Seeded From UniProt

complete

involved_in

GO:0031954

positive regulation of protein autophosphorylation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000908679
UniProtKB:P01127
UniProtKB:P04085

P

Seeded From UniProt

complete

involved_in

GO:0030335

positive regulation of cell migration

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97528
PANTHER:PTN000180420
UniProtKB:B1H0W5
UniProtKB:P01127
UniProtKB:P04085

P

Seeded From UniProt

complete

involved_in

GO:0014068

positive regulation of phosphatidylinositol 3-kinase signaling

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97528
PANTHER:PTN000180420
UniProtKB:P01127
UniProtKB:P04085

P

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1859631
MGI:MGI:97527
PANTHER:PTN000908679
RGD:3282
UniProtKB:P01127
UniProtKB:P04085
UniProtKB:Q9NRA1

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97527
PANTHER:PTN000908679
RGD:3283
RGD:621880
UniProtKB:P04085
UniProtKB:Q9NRA1

C

Seeded From UniProt

complete

enables

GO:0005161

platelet-derived growth factor receptor binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1859631
PANTHER:PTN000180420
UniProtKB:P01127
UniProtKB:P04085
UniProtKB:Q9NRA1

F

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

involved_in

GO:0120162

positive regulation of cold-induced thermogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CI19
ensembl:ENSMUSP00000029652

P

Seeded From UniProt

complete

involved_in

GO:0071230

cellular response to amino acid stimulus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CI19
ensembl:ENSMUSP00000029652

P

Seeded From UniProt

complete

involved_in

GO:0060348

bone development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CI19
ensembl:ENSMUSP00000029652

P

Seeded From UniProt

complete

involved_in

GO:0050730

regulation of peptidyl-tyrosine phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CI19
ensembl:ENSMUSP00000029652

P

Seeded From UniProt

complete

involved_in

GO:0048565

digestive tract development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CI19
ensembl:ENSMUSP00000029652

P

Seeded From UniProt

complete

involved_in

GO:0048008

platelet-derived growth factor receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CI19
ensembl:ENSMUSP00000029652

P

Seeded From UniProt

complete

involved_in

GO:0009887

animal organ morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CI19
ensembl:ENSMUSP00000029652

P

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CI19
ensembl:ENSMUSP00000029652

P

Seeded From UniProt

complete

involved_in

GO:0007171

activation of transmembrane receptor protein tyrosine kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CI19
ensembl:ENSMUSP00000029652

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CI19
ensembl:ENSMUSP00000029652

C

Seeded From UniProt

complete

enables

GO:0005161

platelet-derived growth factor receptor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CI19
ensembl:ENSMUSP00000029652

F

Seeded From UniProt

complete

involved_in

GO:0048146

positive regulation of fibroblast proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NRA1
ensembl:ENSP00000422464

P

Seeded From UniProt

complete

involved_in

GO:0048008

platelet-derived growth factor receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NRA1
ensembl:ENSP00000422464

P

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NRA1
ensembl:ENSP00000422464

F

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NRA1
ensembl:ENSP00000422464

C

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NRA1
ensembl:ENSP00000422464

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NRA1
ensembl:ENSP00000422464

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NRA1
ensembl:ENSP00000422464

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NRA1
ensembl:ENSP00000422464

C

Seeded From UniProt

complete

enables

GO:0005161

platelet-derived growth factor receptor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NRA1
ensembl:ENSP00000422464

F

Seeded From UniProt

complete

enables

GO:0005161

platelet-derived growth factor receptor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029817

F

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000072

F

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029817

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000072

C

Seeded From UniProt

complete

involved_in

GO:0048008

platelet-derived growth factor receptor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029817

P

Seeded From UniProt

complete

involved_in

GO:0048568

embryonic organ development

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029817

P

Seeded From UniProt

complete

involved_in

GO:0051781

positive regulation of cell division

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0497

P

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0339

F

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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