CHICK:O42108

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	LH-2A (ECO:0000313 with EMBL:BAA21846.1)
Protein Name(s)	LIM homeodomain (ECO:0000313 with EMBL:BAA21846.1)
External Links
UniProt	O42108
EMBL	AB005882
PIR	JC5657
RefSeq	NP_990220.1
UniGene	Gga.411
ProteinModelPortal	O42108
SMR	O42108
GeneID	395705
KEGG	gga:395705
CTD	9355
HOVERGEN	HBG006262
KO	K09373
PhylomeDB	O42108
NextBio	20815775
PRO	PR:O42108
GO	GO:0005634 GO:0043565 GO:0008270 GO:0008045 GO:0006355 GO:0021522
Gene3D	1.10.10.60 2.10.110.10
InterPro	IPR017970 IPR001356 IPR009057 IPR001781
Pfam	PF00046 PF00412
SMART	SM00389 SM00132
SUPFAM	SSF46689
PROSITE	PS00027 PS50071 PS00478 PS50023

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0021522	spinal cord motor neuron differentiation	PMID:19545367^[1]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0008045	motor neuron axon guidance	PMID:19545367^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:2000678	negative regulation of transcription regulatory region DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:2000179	positive regulation of neural precursor cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0060041	retina development in camera-type eye	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0050768	negative regulation of neurogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0048675	axon extension	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0048646	anatomical structure formation involved in morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0045814	negative regulation of gene expression, epigenetic	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0045199	maintenance of epithelial cell apical/basal polarity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	F	Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0022008	neurogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0021987	cerebral cortex development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0021978	telencephalon regionalization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0021772	olfactory bulb development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0021537	telencephalon development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0009953	dorsal/ventral pattern formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	F	Seeded From UniProt	complete
involved_in	GO:0007498	mesoderm development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0007420	brain development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0007411	axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
involved_in	GO:0007399	nervous system development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	C	Seeded From UniProt	complete
enables	GO:0003682	chromatin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	F	Seeded From UniProt	complete
involved_in	GO:0001843	neural tube closure	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	P	Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	F	Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0S2 ensembl:ENSMUSP00000000253	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001356 InterPro:IPR009057	F	Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017970	P	Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017970	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0371	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0539	C	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000401037	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000401037	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Avraham, O et al. (2009) Transcriptional control of axonal guidance and sorting in dorsal interneurons by the Lim-HD proteins Lhx9 and Lhx1. Neural Dev 4 21 PubMed GONUTS page

[PMID:19545367-1] 1.0 ^1.1 Avraham, O et al. (2009) Transcriptional control of axonal guidance and sorting in dorsal interneurons by the Lim-HD proteins Lhx9 and Lhx1. Neural Dev 4 21 PubMed GONUTS page

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CHICK:O42108

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