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CHICK:O42108

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) LH-2A (ECO:0000313 with EMBL:BAA21846.1)
Protein Name(s) LIM homeodomain (ECO:0000313 with EMBL:BAA21846.1)
External Links
UniProt O42108
EMBL AB005882
PIR JC5657
RefSeq NP_990220.1
UniGene Gga.411
ProteinModelPortal O42108
SMR O42108
GeneID 395705
KEGG gga:395705
CTD 9355
HOVERGEN HBG006262
KO K09373
PhylomeDB O42108
NextBio 20815775
PRO PR:O42108
GO GO:0005634
GO:0043565
GO:0008270
GO:0008045
GO:0006355
GO:0021522
Gene3D 1.10.10.60
2.10.110.10
InterPro IPR017970
IPR001356
IPR009057
IPR001781
Pfam PF00046
PF00412
SMART SM00389
SM00132
SUPFAM SSF46689
PROSITE PS00027
PS50071
PS00478
PS50023

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0021522

spinal cord motor neuron differentiation

PMID:19545367[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0008045

motor neuron axon guidance

PMID:19545367[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:2000678

negative regulation of transcription regulatory region DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:2000179

positive regulation of neural precursor cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0060041

retina development in camera-type eye

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0050768

negative regulation of neurogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0048675

axon extension

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0048646

anatomical structure formation involved in morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0045814

negative regulation of gene expression, epigenetic

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0045199

maintenance of epithelial cell apical/basal polarity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

F

Seeded From UniProt

complete

involved_in

GO:0030182

neuron differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0022008

neurogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0021987

cerebral cortex development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0021978

telencephalon regionalization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0021772

olfactory bulb development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0021537

telencephalon development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0009953

dorsal/ventral pattern formation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

enables

GO:0008134

transcription factor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

F

Seeded From UniProt

complete

involved_in

GO:0007498

mesoderm development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0007420

brain development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0007411

axon guidance

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

involved_in

GO:0007399

nervous system development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

C

Seeded From UniProt

complete

enables

GO:0003682

chromatin binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

F

Seeded From UniProt

complete

involved_in

GO:0001843

neural tube closure

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

P

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

F

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0S2
ensembl:ENSMUSP00000000253

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001356
InterPro:IPR009057

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017970

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017970

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0371

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000401037

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000401037

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Avraham, O et al. (2009) Transcriptional control of axonal guidance and sorting in dorsal interneurons by the Lim-HD proteins Lhx9 and Lhx1. Neural Dev 4 21 PubMed GONUTS page