CHICK:MYOG

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	MYOG
Protein Name(s)	Myogenin Myogenic factor
External Links
UniProt	P17920
EMBL	D90157
PIR	B35882
RefSeq	NP_989515.1
UniGene	Gga.8
ProteinModelPortal	P17920
SMR	P17920
STRING	9031.ENSGALP00000000227
Ensembl	ENSGALT00000040709
GeneID	374004
KEGG	gga:374004
CTD	4656
eggNOG	NOG285405
GeneTree	ENSGT00530000063004
HOGENOM	HOG000234799
HOVERGEN	HBG006429
InParanoid	P17920
KO	K18483
OMA	FYQEPHF
PhylomeDB	P17920
Reactome	REACT_244114
NextBio	20813532
PRO	PR:P17920
Proteomes	UP000000539
ExpressionAtlas	P17920
GO	GO:0005634 GO:0032993 GO:0005667 GO:0031490 GO:0001047 GO:0070888 GO:0046982 GO:0000978 GO:0001077 GO:0003700 GO:0071392 GO:0071363 GO:0071285 GO:0042693 GO:0008285 GO:0001503 GO:0071158 GO:0014737 GO:0045663 GO:0010831 GO:0048743 GO:0045944 GO:1901739 GO:0014842 GO:0014894 GO:0014878 GO:0014873 GO:0048741 GO:0014891
Gene3D	4.10.280.10
InterPro	IPR002546 IPR011598
Pfam	PF01586 PF00010
SMART	SM00520 SM00353
SUPFAM	SSF47459
PROSITE	PS50888

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0070888	E-box binding	PMID:8035824^[1]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	PMID:8035824^[1]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:8035824^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042693	muscle cell fate commitment	PMID:8035824^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005667	transcription factor complex	PMID:8035824^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0060290	transdifferentiation	PMID:22510437^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(CL:0000388) results_in_commitment_to:(CL:0000056)	Seeded From UniProt	complete
involved_in	GO:0045445	myoblast differentiation	PMID:22510437^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(UBERON:0010328)	Seeded From UniProt	complete
involved_in	GO:1901739	regulation of myoblast fusion	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12979	P		Seeded From UniProt	complete
involved_in	GO:0071392	cellular response to estradiol stimulus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12979	P		Seeded From UniProt	complete
involved_in	GO:0071158	positive regulation of cell cycle arrest	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12979	P		Seeded From UniProt	complete
involved_in	GO:0048743	positive regulation of skeletal muscle fiber development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12979	P		Seeded From UniProt	complete
involved_in	GO:0045663	positive regulation of myoblast differentiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12979	P		Seeded From UniProt	complete
part_of	GO:0032993	protein-DNA complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20428	C		Seeded From UniProt	complete
enables	GO:0031490	chromatin DNA binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12979	F		Seeded From UniProt	complete
involved_in	GO:0014894	response to denervation involved in regulation of muscle adaptation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12979	P		Seeded From UniProt	complete
involved_in	GO:0014891	striated muscle atrophy	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12979	P		Seeded From UniProt	complete
involved_in	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20428	P		Seeded From UniProt	complete
involved_in	GO:0014873	response to muscle activity involved in regulation of muscle adaptation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20428	P		Seeded From UniProt	complete
involved_in	GO:0014842	regulation of skeletal muscle satellite cell proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12979	P		Seeded From UniProt	complete
involved_in	GO:0014737	positive regulation of muscle atrophy	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12979	P		Seeded From UniProt	complete
involved_in	GO:0010831	positive regulation of myotube differentiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12979	P		Seeded From UniProt	complete
involved_in	GO:0008285	negative regulation of cell population proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12979	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20428	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12979	F		Seeded From UniProt	complete
enables	GO:0070888	E-box binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12979	F		Seeded From UniProt	complete
involved_in	GO:1901741	positive regulation of myoblast fusion	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000164853 UniProtKB:P15172	P		Seeded From UniProt	complete
involved_in	GO:0048743	positive regulation of skeletal muscle fiber development	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97276 PANTHER:PTN000898840	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97252 MGI:MGI:97275 MGI:MGI:97276 PANTHER:PTN000164853 RGD:620432 UniProtKB:P15172 UniProtKB:P15173 UniProtKB:P16075 UniProtKB:P17920 UniProtKB:Q01795 WB:WBGene00001948	P		Seeded From UniProt	complete
involved_in	GO:0045663	positive regulation of myoblast differentiation	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97276 PANTHER:PTN000164853	P		Seeded From UniProt	complete
involved_in	GO:0035914	skeletal muscle cell differentiation	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97252 MGI:MGI:97253 MGI:MGI:97275 PANTHER:PTN000898840 ZFIN:ZDB-GENE-980526-561	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0002922 MGI:MGI:97275 MGI:MGI:97276 PANTHER:PTN000164853 RGD:620432 RGD:631429 WB:WBGene00001948	C		Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97252 MGI:MGI:97253 MGI:MGI:97275 MGI:MGI:97276 PANTHER:PTN000164853 UniProtKB:P15172 UniProtKB:P15173	F		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97275 MGI:MGI:97276 PANTHER:PTN000164853 RGD:620432	F		Seeded From UniProt	complete
involved_in	GO:1901739	regulation of myoblast fusion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0071392	cellular response to estradiol stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0071363	cellular response to growth factor stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0071356	cellular response to tumor necrosis factor	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0071285	cellular response to lithium ion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0071158	positive regulation of cell cycle arrest	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
enables	GO:0070888	E-box binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	F		Seeded From UniProt	complete
involved_in	GO:0048743	positive regulation of skeletal muscle fiber development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0048741	skeletal muscle fiber development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0045663	positive regulation of myoblast differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	F		Seeded From UniProt	complete
enables	GO:0031490	chromatin DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	F		Seeded From UniProt	complete
involved_in	GO:0014902	myotube differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0014894	response to denervation involved in regulation of muscle adaptation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0014891	striated muscle atrophy	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0014842	regulation of skeletal muscle satellite cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0014737	positive regulation of muscle atrophy	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0010831	positive regulation of myotube differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0008285	negative regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0007519	skeletal muscle tissue development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
involved_in	GO:0007517	muscle organ development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	F		Seeded From UniProt	complete
involved_in	GO:0001503	ossification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	P		Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	F		Seeded From UniProt	complete
enables	GO:0000987	proximal promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	F		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	F		Seeded From UniProt	complete
enables	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12979 ensembl:ENSMUSP00000027730	F		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15173 ensembl:ENSP00000241651	P		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15173 ensembl:ENSP00000241651	F		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15173 ensembl:ENSP00000241651	C		Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15173 ensembl:ENSP00000241651	F		Seeded From UniProt	complete
enables	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15173 ensembl:ENSP00000241651	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002546	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002546	C		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002546 InterPro:IPR039704	P		Seeded From UniProt	complete
involved_in	GO:0007517	muscle organ development	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002546 InterPro:IPR039704	P		Seeded From UniProt	complete
enables	GO:0046983	protein dimerization activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011598 InterPro:IPR036638	F		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
involved_in	GO:0007517	muscle organ development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0517	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Dechesne, CA et al. (1994) E-box- and MEF-2-independent muscle-specific expression, positive autoregulation, and cross-activation of the chicken MyoD (CMD1) promoter reveal an indirect regulatory pathway. Mol. Cell. Biol. 14 5474-86 PubMed GONUTS page
↑ ^2.0 ^2.1 Takimoto, A et al. (2012) Direct conversion of tenocytes into chondrocytes by Sox9. Exp. Cell Res. 318 1492-507 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:8035824-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Dechesne, CA et al. (1994) E-box- and MEF-2-independent muscle-specific expression, positive autoregulation, and cross-activation of the chicken MyoD (CMD1) promoter reveal an indirect regulatory pathway. Mol. Cell. Biol. 14 5474-86 PubMed GONUTS page

[PMID:22510437-2] 2.0 ^2.1 Takimoto, A et al. (2012) Direct conversion of tenocytes into chondrocytes by Sox9. Exp. Cell Res. 318 1492-507 PubMed GONUTS page

[PMID:21873635-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:MYOG

Contents

Annotations

Notes

References

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