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CHICK:MYLK

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) Mylk
Protein Name(s) Myosin light chain kinase, smooth muscle

MLCK Telokin Myosin light chain kinase, smooth muscle, deglutamylated form

External Links
UniProt P11799
EMBL X52876
X52876
X52876
M31048
M14953
AF045285
AF045255
AF045256
AF045257
AF045260
AF045259
AF045258
AF045261
AF045263
AF045265
AF045274
AF045273
AF045272
AF045271
AF045270
AF045269
AF045268
AF045267
AF045266
AF045283
AF045282
AF045281
AF045280
AF045279
AF045278
AF045277
AF045276
AF045275
AF045284
AF045264
AF045262
M96655
M88283
M88284
PIR S68235
RefSeq NP_990790.1
UniGene Gga.4091
PDB 1CDL
1QS7
1QTX
1VRK
2O5G
3EVU
3EVV
3O77
3O78
PDBsum 1CDL
1QS7
1QTX
1VRK
2O5G
3EVU
3EVV
3O77
3O78
ProteinModelPortal P11799
SMR P11799
BioGrid 676694
IntAct P11799
BindingDB P11799
ChEMBL CHEMBL3062
PaxDb P11799
PRIDE P11799
GeneID 396445
KEGG gga:396445
CTD 4638
eggNOG COG0515
HOGENOM HOG000049287
HOVERGEN HBG052551
KO K00907
PhylomeDB P11799
BRENDA 2.7.11.18
EvolutionaryTrace P11799
NextBio 20816486
PRO PR:P11799
Proteomes UP000000539
GO GO:0005829
GO:0016020
GO:0005524
GO:0046872
GO:0004687
Gene3D 2.60.40.10
InterPro IPR003961
IPR007110
IPR013783
IPR013098
IPR003599
IPR003598
IPR011009
IPR020675
IPR000719
IPR017441
IPR002290
IPR008271
IPR015725
PANTHER PTHR22964
PTHR22964:SF44
Pfam PF00041
PF07679
PF00069
SMART SM00060
SM00409
SM00408
SM00220
SUPFAM SSF49265
SSF56112
PROSITE PS50853
PS50835
PS00107
PS50011
PS00108

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0071688

striated muscle myosin thick filament assembly

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001790569
ZFIN:ZDB-GENE-030113-2
ZFIN:ZDB-GENE-030616-413

P

Seeded From UniProt

complete

involved_in

GO:0055008

cardiac muscle tissue morphogenesis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98864
PANTHER:PTN001790574
UniProtKB:Q8WZ42

P

Seeded From UniProt

complete

involved_in

GO:0055003

cardiac myofibril assembly

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98864
PANTHER:PTN001790574
UniProtKB:Q8WZ42

P

Seeded From UniProt

complete

enables

GO:0051371

muscle alpha-actinin binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001790569
UniProtKB:Q8WZ42

F

Seeded From UniProt

complete

enables

GO:0051015

actin filament binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001790569
UniProtKB:Q8WZ42

F

Seeded From UniProt

complete

involved_in

GO:0048739

cardiac muscle fiber development

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001790574
UniProtKB:Q8WZ42

P

Seeded From UniProt

complete

involved_in

GO:0045214

sarcomere organization

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0005666
MGI:MGI:102844
MGI:MGI:98864
PANTHER:PTN001790569
UniProtKB:Q8WZ42

P

Seeded From UniProt

complete

part_of

GO:0031430

M band

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1328358
MGI:MGI:1341430
MGI:MGI:2685280
MGI:MGI:98864
PANTHER:PTN001790569
RGD:631436
RGD:631437
UniProtKB:A0A1D5PSF9
UniProtKB:E1BF23
UniProtKB:Q8WZ42

C

Seeded From UniProt

complete

involved_in

GO:0030241

skeletal muscle myosin thick filament assembly

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001790574
UniProtKB:Q8WZ42

P

Seeded From UniProt

complete

involved_in

GO:0030240

skeletal muscle thin filament assembly

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001790574
UniProtKB:Q8WZ42

P

Seeded From UniProt

complete

part_of

GO:0030018

Z disc

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0005666
MGI:MGI:98864
PANTHER:PTN001790569
UniProtKB:Q8WZ42

C

Seeded From UniProt

complete

part_of

GO:0030017

sarcomere

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0005666
FB:FBgn0052311
FB:FBgn0053519
MGI:MGI:102844
MGI:MGI:1328358
MGI:MGI:1341430
MGI:MGI:2685280
MGI:MGI:3045352
MGI:MGI:98864
PANTHER:PTN002492843
RGD:1305950
RGD:631436
RGD:631437
UniProtKB:A0A1D5PSF9
UniProtKB:E1BF23
UniProtKB:P16419
UniProtKB:Q05623
UniProtKB:Q14896
UniProtKB:Q8WZ42
WB:WBGene00004130
WB:WBGene00004732
WB:WBGene00006436
WB:WBGene00006759

C

Seeded From UniProt

complete

enables

GO:0008307

structural constituent of muscle

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0005666
PANTHER:PTN001790569
UniProtKB:Q14896
UniProtKB:Q8WZ42

F

Seeded From UniProt

complete

involved_in

GO:0006936

muscle contraction

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102844
MGI:MGI:1328358
MGI:MGI:1336170
MGI:MGI:1336213
MGI:MGI:1341430
MGI:MGI:98864
PANTHER:PTN001790569
RGD:1305950
UniProtKB:Q8WZ42

P

Seeded From UniProt

complete

part_of

GO:0005865

striated muscle thin filament

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001790569
UniProtKB:Q8WZ42

C

Seeded From UniProt

complete

enables

GO:0004672

protein kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR008271
InterPro:IPR015725

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR017441

F

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR008271
InterPro:IPR015725

P

Seeded From UniProt

complete

enables

GO:0004687

myosin light chain kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.11.18

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0723

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0005516

calmodulin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0112

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0091

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page