CHICK:IGF2

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	IGF2
Protein Name(s)	Insulin-like growth factor II IGF-II
External Links
UniProt	P33717
EMBL	S82962 S82960 AY267181
PIR	A60740 T10897
RefSeq	NP_001025513.1
UniGene	Gga.8511
ProteinModelPortal	P33717
SMR	P33717
PaxDb	P33717
PRIDE	P33717
GeneID	395097
KEGG	gga:395097
CTD	3481
eggNOG	NOG44017
HOGENOM	HOG000233362
HOVERGEN	HBG006137
InParanoid	P33717
KO	K13769
OrthoDB	EOG7TF7CG
PhylomeDB	P33717
TreeFam	TF332820
Reactome	REACT_189769 REACT_189775 REACT_189777 REACT_247929
NextBio	20815190
PRO	PR:P33717
Proteomes	UP000000539
ExpressionAtlas	P33717
GO	GO:0005615 GO:0070062 GO:0043539 GO:0030546 GO:0031017 GO:0038028 GO:0009887 GO:0001649 GO:0042104 GO:2000467 GO:0045725 GO:0046628 GO:0043410 GO:0045840 GO:0050731 GO:0051897 GO:0045944 GO:0051146
Gene3D	1.10.100.10
InterPro	IPR022334 IPR013576 IPR016179 IPR022350 IPR022353 IPR022352
Pfam	PF08365 PF00049
PRINTS	PR02002 PR02006 PR00276
ProDom	PD005188
SMART	SM00078
SUPFAM	SSF56994
PROSITE	PS00262

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P01344	P	Seeded From UniProt	complete
enables	GO:0005178	integrin binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P01344	F	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:2272467^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005179	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0048018	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P	Seeded From UniProt	complete
involved_in	GO:0071902	positive regulation of protein serine/threonine kinase activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0043539	P	Seeded From UniProt	complete
involved_in	GO:0051897	positive regulation of protein kinase B signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01344 ensembl:ENSP00000391826	P	Seeded From UniProt	complete
involved_in	GO:0046628	positive regulation of insulin receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01344 ensembl:ENSP00000391826	P	Seeded From UniProt	complete
involved_in	GO:0045840	positive regulation of mitotic nuclear division	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01344 ensembl:ENSP00000391826	P	Seeded From UniProt	complete
involved_in	GO:0043410	positive regulation of MAPK cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01344 ensembl:ENSP00000391826	P	Seeded From UniProt	complete
involved_in	GO:0042104	positive regulation of activated T cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01344 ensembl:ENSP00000391826	P	Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01344 ensembl:ENSP00000391826	P	Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01344 ensembl:ENSP00000391826	F	Seeded From UniProt	complete
enables	GO:0005178	integrin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01344 ensembl:ENSP00000391826	F	Seeded From UniProt	complete
enables	GO:0005159	insulin-like growth factor receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01344 ensembl:ENSP00000391826	F	Seeded From UniProt	complete
enables	GO:0005158	insulin receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01344 ensembl:ENSP00000391826	F	Seeded From UniProt	complete
involved_in	GO:2000467	positive regulation of glycogen (starch) synthase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
involved_in	GO:0051147	regulation of muscle cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
involved_in	GO:0051146	striated muscle cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
involved_in	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
enables	GO:0048018	receptor ligand activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	F	Seeded From UniProt	complete
involved_in	GO:0046628	positive regulation of insulin receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
involved_in	GO:0045725	positive regulation of glycogen biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
enables	GO:0043539	protein serine/threonine kinase activator activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	F	Seeded From UniProt	complete
involved_in	GO:0043085	positive regulation of catalytic activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
involved_in	GO:0040018	positive regulation of multicellular organism growth	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
involved_in	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
involved_in	GO:0031056	regulation of histone modification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
involved_in	GO:0031017	exocrine pancreas development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
involved_in	GO:0009887	animal organ morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	C	Seeded From UniProt	complete
enables	GO:0005159	insulin-like growth factor receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	F	Seeded From UniProt	complete
involved_in	GO:0001934	positive regulation of protein phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
involved_in	GO:0001649	osteoblast differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P09535 ensembl:ENSMUSP00000114076	P	Seeded From UniProt	complete
enables	GO:0005179	hormone activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016179 InterPro:IPR022350 InterPro:IPR022352	F	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016179	C	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR022334 InterPro:IPR022350	C	Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR022334 InterPro:IPR022350	F	Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0339	F	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C	Seeded From UniProt	complete
involved_in	GO:0051781	positive regulation of cell division	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0497	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Ballard, FJ et al. (1990) Chicken insulin-like growth factor-I: amino acid sequence, radioimmunoassay, and plasma levels between strains and during growth. Gen. Comp. Endocrinol. 79 459-68 PubMed GONUTS page

[PMID:2272467-1] Ballard, FJ et al. (1990) Chicken insulin-like growth factor-I: amino acid sequence, radioimmunoassay, and plasma levels between strains and during growth. Gen. Comp. Endocrinol. 79 459-68 PubMed GONUTS page

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CHICK:IGF2

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