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CHICK:IFNB

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) IFNB (synonyms: IFN2)
Protein Name(s) Interferon type B

IFN-beta

External Links
UniProt Q90873
EMBL X92479
AY974089
RefSeq NP_001020007.1
UniGene Gga.22865
ProteinModelPortal Q90873
STRING 9031.ENSGALP00000038687
Ensembl ENSGALT00000039477
GeneID 554219
KEGG gga:554219
CTD 554219
eggNOG NOG276534
GeneTree ENSGT00730000111684
HOGENOM HOG000208434
HOVERGEN HBG052087
InParanoid Q90873
KO K05415
OMA SINKYFR
OrthoDB EOG7WMCKW
PhylomeDB Q90873
TreeFam TF336177
NextBio 20880732
PRO PR:Q90873
Proteomes UP000000539
GO GO:0005615
GO:0005125
GO:0005132
GO:0002250
GO:0030183
GO:0042100
GO:0019221
GO:0051607
GO:0006959
GO:0002323
GO:0045918
GO:0033141
GO:2000379
GO:0034141
GO:0043330
GO:0002286
Gene3D 1.20.1250.10
InterPro IPR009079
IPR012351
IPR000471
PANTHER PTHR11691
Pfam PF00143
SMART SM00076
SUPFAM SSF47266
PROSITE PS00252

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:2000379

positive regulation of reactive oxygen species metabolic process

PMID:18593329[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0051607

defense response to virus

PMID:18593329[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045918

negative regulation of cytolysis

PMID:18593329[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0034141

positive regulation of toll-like receptor 3 signaling pathway

PMID:18593329[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

PMID:19776194[2]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0043330

response to exogenous dsRNA

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000914537
UniProtKB:P01574

P

Seeded From UniProt

complete

involved_in

GO:0042100

B cell proliferation

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107657
PANTHER:PTN000914537

P

Seeded From UniProt

complete

involved_in

GO:0033141

positive regulation of peptidyl-serine phosphorylation of STAT protein

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000914537
UniProtKB:P01574

P

Seeded From UniProt

complete

involved_in

GO:0030183

B cell differentiation

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2448469
PANTHER:PTN000914537

P

Seeded From UniProt

complete

involved_in

GO:0019221

cytokine-mediated signaling pathway

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2448469
PANTHER:PTN000914537
UniProtKB:Q9P0W0

P

Seeded From UniProt

complete

involved_in

GO:0006959

humoral immune response

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107657
PANTHER:PTN000914537

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107657
MGI:MGI:107659
MGI:MGI:107662
MGI:MGI:107664
MGI:MGI:107668
PANTHER:PTN000914537

C

Seeded From UniProt

complete

enables

GO:0005132

type I interferon receptor binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107657
MGI:MGI:2448469
PANTHER:PTN000914537
UniProtKB:Q9P0W0

F

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107657
MGI:MGI:107668
PANTHER:PTN000914537
UniProtKB:P01574

F

Seeded From UniProt

complete

involved_in

GO:0002323

natural killer cell activation involved in immune response

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107659
MGI:MGI:107664
MGI:MGI:107668
PANTHER:PTN000914537

P

Seeded From UniProt

complete

involved_in

GO:0002286

T cell activation involved in immune response

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107668
PANTHER:PTN000914537

P

Seeded From UniProt

complete

involved_in

GO:0002250

adaptive immune response

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107657
PANTHER:PTN000914537

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

enables

GO:0005126

cytokine receptor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000471

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000471

C

Seeded From UniProt

complete

involved_in

GO:0006952

defense response

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000471

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0202

C

Seeded From UniProt

complete

involved_in

GO:0051607

defense response to virus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0051

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0202

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Karpala, AJ et al. (2008) Molecular cloning, expression, and characterization of chicken IFN -lambda. J. Interferon Cytokine Res. 28 341-50 PubMed GONUTS page
  2. Lu, Y et al. (2009) Expression profiles of genes in Toll-like receptor-mediated signaling of broilers infected with Clostridium perfringens. Clin. Vaccine Immunol. 16 1639-47 PubMed GONUTS page
  3. 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page