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CHICK:HPSE

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) HPSE (synonyms: HPA)
Protein Name(s) Heparanase
External Links
UniProt Q90YK5
EMBL AY037007
RefSeq NP_989498.1
UniGene Gga.950
ProteinModelPortal Q90YK5
STRING 9031.ENSGALP00000018245
CAZy GH79
PaxDb Q90YK5
GeneID 373981
KEGG gga:373981
CTD 10855
eggNOG NOG72789
HOGENOM HOG000007256
HOVERGEN HBG081606
InParanoid Q90YK5
KO K07964
PhylomeDB Q90YK5
NextBio 20813510
PRO PR:Q90YK5
Proteomes UP000000539
GO GO:0005576
GO:0016020
GO:0030305
GO:0007160
GO:0030200
InterPro IPR005199
IPR017853
PANTHER PTHR14363
Pfam PF03662
SUPFAM SSF51445

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0030305

heparanase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y251

F

Seeded From UniProt

complete

involved_in

GO:0030200

heparan sulfate proteoglycan catabolic process

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y251

P

Seeded From UniProt

complete

involved_in

GO:0007160

cell-matrix adhesion

PMID:12773484[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0060055

angiogenesis involved in wound healing

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1343124
PANTHER:PTN000372532

P

Seeded From UniProt

complete

part_of

GO:0031012

extracellular matrix

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001024081
UniProtKB:Q8WWQ2

C

Seeded From UniProt

complete

involved_in

GO:0007160

cell-matrix adhesion

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000372532
UniProtKB:Q90YK5
UniProtKB:Q9Y251

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005199

C

Seeded From UniProt

complete

enables

GO:0016798

hydrolase activity, acting on glycosyl bonds

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005199

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0130

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Goldshmidt, O et al. (2003) Heparanase mediates cell adhesion independent of its enzymatic activity. FASEB J. 17 1015-25 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page