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CHICK:HES1
Contents
| Species (Taxon ID) | Gallus gallus (Chicken). (9031) | |
| Gene Name(s) | HES1 (synonyms: HAIRY1) | |
| Protein Name(s) | Transcription factor HES-1
C-HAIRY1 Hairy and enhancer of split 1 | |
| External Links | ||
| UniProt | O57337 | |
| EMBL | AF032966 | |
| UniGene | Gga.3754 Gga.51069 | |
| ProteinModelPortal | O57337 | |
| PaxDb | O57337 | |
| eggNOG | NOG319418 | |
| HOGENOM | HOG000236346 | |
| HOVERGEN | HBG005960 | |
| InParanoid | O57337 | |
| PhylomeDB | O57337 | |
| NextBio | 20815220 | |
| PRO | PR:O57337 | |
| Proteomes | UP000000539 | |
| GO | GO:0005634 GO:0003677 GO:0006355 GO:0006351 | |
| Gene3D | 4.10.280.10 | |
| InterPro | IPR011598 IPR003650 | |
| Pfam | PF07527 PF00010 | |
| SMART | SM00353 SM00511 | |
| SUPFAM | SSF47459 | |
| PROSITE | PS50888 PS51054 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0045665 |
negative regulation of neuron differentiation |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:1990837 |
sequence-specific double-stranded DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0002609 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0050767 |
regulation of neurogenesis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:104853 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000591 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1859852 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008134 |
transcription factor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0001168 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007219 |
Notch signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0010109 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0002631 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003714 |
transcription corepressor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1097714 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001756 |
somitogenesis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2135679 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000977 |
RNA polymerase II regulatory region sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1859852 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0046982 |
protein heterodimerization activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1903507 |
negative regulation of nucleic acid-templated transcription |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0003714 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046983 |
protein dimerization activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Bai, G et al. (2007) Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1. Dev. Cell 13 283-97 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 2.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 Leimeister, C et al. (2000) Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors. Dev. Biol. 227 91-103 PubMed GONUTS page
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