CHICK:GATA6

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	GATA6
Protein Name(s)	Transcription factor GATA-6 GATA-binding factor 6
External Links
UniProt	P43693
EMBL	U11889
PIR	I50703
RefSeq	NP_990751.1
UniGene	Gga.2061
ProteinModelPortal	P43693
SMR	P43693
STRING	9031.ENSGALP00000024112
PaxDb	P43693
GeneID	396390
KEGG	gga:396390
CTD	2627
eggNOG	COG5641
HOGENOM	HOG000047700
HOVERGEN	HBG051703
InParanoid	P43693
KO	K17897
PhylomeDB	P43693
Reactome	REACT_286472
NextBio	20816432
PRO	PR:P43693
Proteomes	UP000000539
ExpressionAtlas	P43693
GO	GO:0005634 GO:0005667 GO:0003682 GO:0000979 GO:0003705 GO:0008270 GO:0055007 GO:0014898 GO:0060947 GO:0071773 GO:0071371 GO:0071456 GO:0060486 GO:0007493 GO:0060575 GO:0001889 GO:0060430 GO:0008584 GO:0043066 GO:0000122 GO:0032911 GO:0032912 GO:0048645 GO:0003148 GO:0003310 GO:0006644 GO:0045766 GO:0060045 GO:0051891 GO:0071158 GO:0045944 GO:0042493 GO:0043627 GO:0006366 GO:0035239 GO:0003309 GO:0060510
Gene3D	3.30.50.10
InterPro	IPR008013 IPR016375 IPR028437 IPR000679 IPR013088
PANTHER	PTHR10071:SF23
Pfam	PF00320 PF05349
PIRSF	PIRSF003028
PRINTS	PR00619
SMART	SM00401
PROSITE	PS00344 PS50114

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0005634	nucleus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q92908	C	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q92908	P	Seeded From UniProt	complete
involved_in	GO:0030855	epithelial cell differentiation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107516 PANTHER:PTN002560167 UniProtKB:Q92908	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0003117 FB:FBgn0032223 FB:FBgn0038391 MGI:MGI:107516 MGI:MGI:109497 MGI:MGI:95661 MGI:MGI:95662 MGI:MGI:95663 MGI:MGI:95664 PANTHER:PTN001600628 PomBase:SPAC23E2.01 PomBase:SPCC1902.01 RGD:2663 RGD:2664 RGD:2665 RGD:2666 RGD:621250 SGD:S000000842 SGD:S000001742 SGD:S000001873 SGD:S000003646 UniProtKB:E1C9C6 UniProtKB:I3LUZ9 UniProtKB:P15976 UniProtKB:P17429 UniProtKB:P23769 UniProtKB:P23771 UniProtKB:P43691 UniProtKB:P43692 UniProtKB:P43694 UniProtKB:Q92908 UniProtKB:Q9BWX5 WB:WBGene00001186 WB:WBGene00001249 WB:WBGene00001250 WB:WBGene00001251 WB:WBGene00001252 WB:WBGene00001253 WB:WBGene00001310 WB:WBGene00001311 WB:WBGene00015981 ZFIN:ZDB-GENE-980526-340	C	Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0003117 MGI:MGI:95661 MGI:MGI:95664 PANTHER:PTN001600628 RGD:2665 SGD:S000001742 SGD:S000003646 UniProtKB:P23769 UniProtKB:P43694 UniProtKB:Q92908 WB:WBGene00001249 WB:WBGene00001310	F	Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107516 MGI:MGI:95661 MGI:MGI:95662 MGI:MGI:95663 MGI:MGI:95664 PANTHER:PTN001600628 PomBase:SPAC23E2.01 PomBase:SPCC1902.01 SGD:S000000842 UniProtKB:P15976 UniProtKB:P23771	F	Seeded From UniProt	complete
involved_in	GO:0071773	cellular response to BMP stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0071371	cellular response to gonadotropin stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0060510	type II pneumocyte differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0060486	Clara cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0060430	lung saccule development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0060045	positive regulation of cardiac muscle cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0055007	cardiac muscle cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0051891	positive regulation of cardioblast differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0048738	cardiac muscle tissue development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0048645	animal organ formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0043627	response to estrogen	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	F	Seeded From UniProt	complete
involved_in	GO:0035987	endodermal cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0035239	tube morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0031016	pancreas development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0030855	epithelial cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0014898	cardiac muscle hypertrophy in response to stress	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0010468	regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	F	Seeded From UniProt	complete
involved_in	GO:0007493	endodermal cell fate determination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0006644	phospholipid metabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
part_of	GO:0005667	transcription factor complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	C	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	F	Seeded From UniProt	complete
enables	GO:0003682	chromatin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	F	Seeded From UniProt	complete
involved_in	GO:0003310	pancreatic A cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0003309	type B pancreatic cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
involved_in	GO:0001889	liver development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	P	Seeded From UniProt	complete
enables	GO:0001103	RNA polymerase II repressing transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	F	Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	F	Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q61169 ensembl:ENSMUSP00000041774	F	Seeded From UniProt	complete
involved_in	GO:0110024	positive regulation of cardiac muscle myoblast proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
involved_in	GO:0071456	cellular response to hypoxia	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
involved_in	GO:0071158	positive regulation of cell cycle arrest	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
involved_in	GO:0070848	response to growth factor	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
involved_in	GO:0060947	cardiac vascular smooth muscle cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
involved_in	GO:0060575	intestinal epithelial cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
involved_in	GO:0051145	smooth muscle cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
involved_in	GO:0045766	positive regulation of angiogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	F	Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
involved_in	GO:0042493	response to drug	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
involved_in	GO:0032912	negative regulation of transforming growth factor beta2 production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
involved_in	GO:0032911	negative regulation of transforming growth factor beta1 production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
part_of	GO:0031965	nuclear membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	C	Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	F	Seeded From UniProt	complete
involved_in	GO:0008584	male gonad development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	F	Seeded From UniProt	complete
involved_in	GO:0006366	transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	C	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	F	Seeded From UniProt	complete
involved_in	GO:0003148	outflow tract septum morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	F	Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q92908 ensembl:ENSP00000269216	P	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008013	F	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR039355	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008013	C	Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000679 InterPro:IPR013088 InterPro:IPR016375	P	Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000679 InterPro:IPR008013 InterPro:IPR013088 InterPro:IPR039355	F	Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000679	F	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008013	P	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[1]

CHICK:GATA6

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