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CHICK:FYN

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) FYN
Protein Name(s) Tyrosine-protein kinase Fyn

Proto-oncogene c-Fyn p59-Fyn

External Links
UniProt Q05876
EMBL X52841
PIR S33568
UniGene Gga.48382
PDB 2L2P
2LP5
3CQT
PDBsum 2L2P
2LP5
3CQT
ProteinModelPortal Q05876
SMR Q05876
DIP DIP-738N
MINT MINT-7222020
PaxDb Q05876
PRIDE Q05876
CTD 2534
eggNOG COG0515
HOGENOM HOG000233858
HOVERGEN HBG008761
InParanoid Q05876
PhylomeDB Q05876
BRENDA 2.7.10.2
Reactome REACT_277627
REACT_305550
EvolutionaryTrace Q05876
NextBio 20816344
PRO PR:Q05876
Proteomes UP000000539
GO GO:0005829
GO:0005524
GO:0046872
GO:0004715
GO:0004672
GO:0004713
GO:0015631
GO:0030900
GO:0001764
GO:0018108
GO:0008360
Gene3D 3.30.505.10
InterPro IPR011009
IPR000719
IPR017441
IPR001245
IPR000980
IPR001452
IPR008266
IPR020635
Pfam PF07714
PF00017
PF00018
PRINTS PR00401
PR00452
PR00109
SMART SM00252
SM00326
SM00219
SUPFAM SSF50044
SSF55550
SSF56112
PROSITE PS00107
PS50011
PS00109
PS50001
PS50002

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005623

cell

PMID:19139104[1]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0000955)

Seeded From UniProt

complete

part_of

GO:0045121

membrane raft

PMID:19139104[1]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000740)

Seeded From UniProt

complete

involved_in

GO:0030900

forebrain development

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P39688

P

Seeded From UniProt

complete

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q62844

P

Seeded From UniProt

complete

enables

GO:0015631

tubulin binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P39688

F

Seeded From UniProt

complete

involved_in

GO:0008360

regulation of cell shape

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P39688

P

Seeded From UniProt

complete

enables

GO:0004713

protein tyrosine kinase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P39688

F

Seeded From UniProt

complete

enables

GO:0004672

protein kinase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P39688

F

Seeded From UniProt

complete

involved_in

GO:0001764

neuron migration

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P39688

P

Seeded From UniProt

complete

involved_in

GO:0050852

T cell receptor signaling pathway

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002521487
UniProtKB:P06241

P

Seeded From UniProt

complete

involved_in

GO:0038083

peptidyl-tyrosine autophosphorylation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002521528
UniProtKB:Q9H3Y6
WB:WBGene00005077

P

Seeded From UniProt

complete

part_of

GO:0031234

extrinsic component of cytoplasmic side of plasma membrane

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002521528
UniProtKB:P08631

C

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002521528
RGD:621423

P

Seeded From UniProt

complete

involved_in

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002521528
UniProtKB:P07948

P

Seeded From UniProt

complete

enables

GO:0005102

signaling receptor binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0262733
PANTHER:PTN002521528
RGD:2641
RGD:620795
RGD:621017
UniProtKB:P12931

F

Seeded From UniProt

complete

enables

GO:0004715

non-membrane spanning protein tyrosine kinase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95527
PANTHER:PTN002521528
UniProtKB:P09769
UniProtKB:P51451
UniProtKB:Q13882
WB:WBGene00005077

F

Seeded From UniProt

complete

enables

GO:0004672

protein kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR008266

F

Seeded From UniProt

complete

enables

GO:0004713

protein tyrosine kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020635

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR017441

F

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR008266
InterPro:IPR020635

P

Seeded From UniProt

complete

enables

GO:0004715

non-membrane spanning protein tyrosine kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.10.2

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-GGA-3928596
Reactome:R-GGA-3928579

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0004713

protein tyrosine kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0829

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Ramseger, R et al. (2009) Transmembrane form agrin-induced process formation requires lipid rafts and the activation of Fyn and MAPK. J. Biol. Chem. 284 7697-705 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page