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CHICK:FGFR1

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) FGFR1 (synonyms: CEK1)
Protein Name(s) Fibroblast growth factor receptor 1

FGFR-1 bFGF-R-1 Basic fibroblast growth factor receptor 1 Tyrosine kinase receptor CEK1

External Links
UniProt P21804
EMBL M24637
PIR A41345
RefSeq NP_990841.1
UniGene Gga.870
ProteinModelPortal P21804
SMR P21804
PaxDb P21804
GeneID 396516
KEGG gga:396516
CTD 2260
eggNOG COG0515
HOVERGEN HBG000345
InParanoid P21804
KO K04362
PhylomeDB P21804
BRENDA 2.7.10.1
NextBio 20816553
PRO PR:P21804
Proteomes UP000000539
GO GO:0016023
GO:0005829
GO:0016021
GO:0005634
GO:0005886
GO:0005524
GO:0017134
GO:0005007
GO:0008201
GO:0003347
GO:0018108
GO:0008284
GO:0043406
GO:0010863
GO:0045893
Gene3D 2.60.40.10
InterPro IPR028174
IPR016248
IPR007110
IPR013783
IPR013098
IPR003598
IPR013151
IPR011009
IPR000719
IPR017441
IPR001245
IPR008266
IPR020635
PANTHER PTHR24416:SF131
Pfam PF07679
PF00047
PF07714
PIRSF PIRSF000628
PRINTS PR00109
SMART SM00408
SM00219
SUPFAM SSF56112
PROSITE PS50835
PS00107
PS50011
PS00109

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0043406

positive regulation of MAP kinase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P11362

P

Seeded From UniProt

complete

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P11362

P

Seeded From UniProt

complete

enables

GO:0017134

fibroblast growth factor binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P11362

F

Seeded From UniProt

complete

involved_in

GO:0010863

positive regulation of phospholipase C activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P11362

P

Seeded From UniProt

complete

enables

GO:0008201

heparin binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P11362

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P11362

C

Seeded From UniProt

complete

enables

GO:0005007

fibroblast growth factor-activated receptor activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P11362

F

Seeded From UniProt

complete

involved_in

GO:0045597

positive regulation of cell differentiation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95522
PANTHER:PTN000699302
RGD:620713
UniProtKB:P11362

P

Seeded From UniProt

complete

part_of

GO:0043235

receptor complex

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0015380
FB:FBgn0024245
FB:FBgn0033791
PANTHER:PTN002356460
UniProtKB:A6QR62
UniProtKB:O15146
UniProtKB:P00533
UniProtKB:P04626
UniProtKB:P04629
UniProtKB:P06213
UniProtKB:P07949
UniProtKB:P08069
UniProtKB:P11362
UniProtKB:P14616
UniProtKB:P17948
UniProtKB:P21860
UniProtKB:P35916
UniProtKB:Q01973
UniProtKB:Q08345
UniProtKB:Q15303
UniProtKB:Q16288
UniProtKB:Q16620

C

Seeded From UniProt

complete

enables

GO:0017134

fibroblast growth factor binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95522
MGI:MGI:95523
PANTHER:PTN000699279
RGD:2611
RGD:620714
UniProtKB:P11362
UniProtKB:P21802
UniProtKB:P22455
UniProtKB:P22607
ZFIN:ZDB-GENE-030323-1

F

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95522
MGI:MGI:95523
MGI:MGI:95524
MGI:MGI:95525
PANTHER:PTN001230353
RGD:620714
UniProtKB:P11362
UniProtKB:P21802
UniProtKB:P22455
UniProtKB:P22607

P

Seeded From UniProt

complete

involved_in

GO:0007399

nervous system development

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95522
PANTHER:PTN001562203
RGD:620713
UniProtKB:P11362
ZFIN:ZDB-GENE-980526-255

P

Seeded From UniProt

complete

involved_in

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003366
FB:FBgn0003731
FB:FBgn0003733
FB:FBgn0283499
MGI:MGI:104757
MGI:MGI:109378
MGI:MGI:1096337
MGI:MGI:1339758
MGI:MGI:1345277
MGI:MGI:95276
MGI:MGI:95278
MGI:MGI:95294
MGI:MGI:95522
MGI:MGI:95523
MGI:MGI:95524
MGI:MGI:95525
MGI:MGI:95558
MGI:MGI:95561
MGI:MGI:96575
MGI:MGI:96677
MGI:MGI:96683
MGI:MGI:96969
MGI:MGI:97384
MGI:MGI:97530
MGI:MGI:97531
MGI:MGI:97902
MGI:MGI:98277
MGI:MGI:99216
MGI:MGI:99611
MGI:MGI:99612
MGI:MGI:99654
PANTHER:PTN002356460
RGD:2543
RGD:2611
RGD:2612
RGD:2621
RGD:2869
RGD:2917
RGD:2965
RGD:3082
RGD:3213
RGD:3214
RGD:3284
RGD:3285
RGD:620144
RGD:620714
RGD:620831
RGD:621737
RGD:69323
UniProtKB:A6QR62
UniProtKB:P00533
UniProtKB:P04626
UniProtKB:P04629
UniProtKB:P06213
UniProtKB:P07949
UniProtKB:P08069
UniProtKB:P09619
UniProtKB:P10721
UniProtKB:P11362
UniProtKB:P16234
UniProtKB:P17948
UniProtKB:P21709
UniProtKB:P21802
UniProtKB:P22455
UniProtKB:P22607
UniProtKB:P29317
UniProtKB:P29320
UniProtKB:P35916
UniProtKB:P35968
UniProtKB:P54753
UniProtKB:P54760
UniProtKB:P54762
UniProtKB:P54764
UniProtKB:Q02763
UniProtKB:Q08345
UniProtKB:Q15303
UniProtKB:Q15375
UniProtKB:Q16288
UniProtKB:Q16620
UniProtKB:Q16832
UniProtKB:Q5JZY3
UniProtKB:Q91987
WB:WBGene00001184
WB:WBGene00006868
ZFIN:ZDB-GENE-020503-1
ZFIN:ZDB-GENE-020503-2
ZFIN:ZDB-GENE-060503-14
ZFIN:ZDB-GENE-070713-2
ZFIN:ZDB-GENE-980526-255
ZFIN:ZDB-GENE-980526-326
ZFIN:ZDB-GENE-990415-62

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003366
FB:FBgn0003731
FB:FBgn0003733
FB:FBgn0011829
FB:FBgn0015380
FB:FBgn0032006
FB:FBgn0283499
MGI:MGI:103581
MGI:MGI:104771
MGI:MGI:109378
MGI:MGI:98277
MGI:MGI:99611
PANTHER:PTN002356460
RGD:1560587
RGD:3213
RGD:3214
RGD:70957
UniProtKB:P04629
UniProtKB:P06213
UniProtKB:P07949
UniProtKB:P16234
UniProtKB:P17948
UniProtKB:P21709
UniProtKB:P21802
UniProtKB:P22455
UniProtKB:P22607
UniProtKB:P29317
UniProtKB:P29320
UniProtKB:P35968
UniProtKB:P54753
UniProtKB:P54760
UniProtKB:P54762
UniProtKB:Q02763
UniProtKB:Q16620
UniProtKB:Q9UM73
WB:WBGene00000289
WB:WBGene00000898

C

Seeded From UniProt

complete

enables

GO:0005007

fibroblast growth factor-activated receptor activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95522
MGI:MGI:95524
PANTHER:PTN000699279
RGD:2611
RGD:620714
UniProtKB:P11362
UniProtKB:P21802
UniProtKB:P22455
UniProtKB:P22607
ZFIN:ZDB-GENE-980526-255

F

Seeded From UniProt

complete

enables

GO:0004714

transmembrane receptor protein tyrosine kinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003733
FB:FBgn0040505
FB:FBgn0283499
MGI:MGI:109378
MGI:MGI:1339758
MGI:MGI:1345277
MGI:MGI:95276
MGI:MGI:95294
MGI:MGI:95522
MGI:MGI:95524
MGI:MGI:95558
MGI:MGI:95561
MGI:MGI:96677
MGI:MGI:96683
MGI:MGI:96969
MGI:MGI:97384
MGI:MGI:97530
MGI:MGI:97902
MGI:MGI:98277
MGI:MGI:99611
MGI:MGI:99612
MGI:MGI:99654
PANTHER:PTN002356460
RGD:2543
RGD:2611
RGD:2621
RGD:2869
RGD:2917
RGD:2965
RGD:3082
RGD:3213
RGD:3214
RGD:3284
RGD:3285
RGD:620144
RGD:620714
RGD:620831
RGD:621737
UniProtKB:P00533
UniProtKB:P04626
UniProtKB:P04629
UniProtKB:P06213
UniProtKB:P07333
UniProtKB:P07949
UniProtKB:P08069
UniProtKB:P09619
UniProtKB:P10721
UniProtKB:P11362
UniProtKB:P14616
UniProtKB:P16234
UniProtKB:P17948
UniProtKB:P21709
UniProtKB:P21802
UniProtKB:P22455
UniProtKB:P22607
UniProtKB:P29317
UniProtKB:P29320
UniProtKB:P35916
UniProtKB:P35968
UniProtKB:P54753
UniProtKB:P54760
UniProtKB:P54762
UniProtKB:Q08345
UniProtKB:Q15303
UniProtKB:Q16620
UniProtKB:Q16832
UniProtKB:Q5JZY3
UniProtKB:Q91987
UniProtKB:Q9UM73
WB:WBGene00000289
WB:WBGene00006868
WB:WBGene00020504
ZFIN:ZDB-GENE-980526-255

F

Seeded From UniProt

complete

involved_in

GO:2000546

positive regulation of endothelial cell chemotaxis to fibroblast growth factor

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

P

Seeded From UniProt

complete

involved_in

GO:1905564

positive regulation of vascular endothelial cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

P

Seeded From UniProt

complete

enables

GO:0090722

receptor-receptor interaction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

F

Seeded From UniProt

complete

involved_in

GO:0046777

protein autophosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

P

Seeded From UniProt

complete

involved_in

GO:0045666

positive regulation of neuron differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

P

Seeded From UniProt

complete

involved_in

GO:0043536

positive regulation of blood vessel endothelial cell migration

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

P

Seeded From UniProt

complete

involved_in

GO:0043410

positive regulation of MAPK cascade

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

P

Seeded From UniProt

complete

involved_in

GO:0043406

positive regulation of MAP kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

P

Seeded From UniProt

complete

part_of

GO:0043235

receptor complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

C

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

F

Seeded From UniProt

complete

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

P

Seeded From UniProt

complete

enables

GO:0017134

fibroblast growth factor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

F

Seeded From UniProt

complete

involved_in

GO:0010863

positive regulation of phospholipase C activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

P

Seeded From UniProt

complete

involved_in

GO:0008543

fibroblast growth factor receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

P

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

P

Seeded From UniProt

complete

enables

GO:0008201

heparin binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

C

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

C

Seeded From UniProt

complete

enables

GO:0005007

fibroblast growth factor-activated receptor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

F

Seeded From UniProt

complete

enables

GO:0004713

protein tyrosine kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11362
ensembl:ENSP00000393312

F

Seeded From UniProt

complete

involved_in

GO:2001239

regulation of extrinsic apoptotic signaling pathway in absence of ligand

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:2000830

positive regulation of parathyroid hormone secretion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:1903465

positive regulation of mitotic cell cycle DNA replication

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0090272

negative regulation of fibroblast growth factor production

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0090080

positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0070640

vitamin D3 metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0060665

regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0060484

lung-associated mesenchyme development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0060445

branching involved in salivary gland morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0060117

auditory receptor cell development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0060045

positive regulation of cardiac muscle cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0051174

regulation of phosphorus metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0048762

mesenchymal cell differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0048699

generation of neurons

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0048514

blood vessel morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0048469

cell maturation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0048378

regulation of lateral mesodermal cell fate specification

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0048339

paraxial mesoderm development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0045787

positive regulation of cell cycle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0043583

ear development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0042474

middle ear morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0042473

outer ear morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0042472

inner ear morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

enables

GO:0042169

SH2 domain binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

F

Seeded From UniProt

complete

involved_in

GO:0042127

regulation of cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0035607

fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0030901

midbrain development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0030326

embryonic limb morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0030324

lung development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0021847

ventricular zone neuroblast division

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0021769

orbitofrontal cortex development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

enables

GO:0017134

fibroblast growth factor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

F

Seeded From UniProt

complete

involved_in

GO:0010976

positive regulation of neuron projection development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0010966

regulation of phosphate transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0010629

negative regulation of gene expression

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0010468

regulation of gene expression

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0008543

fibroblast growth factor receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0007605

sensory perception of sound

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0007435

salivary gland morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0007420

brain development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

C

Seeded From UniProt

complete

enables

GO:0005007

fibroblast growth factor-activated receptor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

F

Seeded From UniProt

complete

involved_in

GO:0002062

chondrocyte differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0002053

positive regulation of mesenchymal cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0001759

organ induction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0001657

ureteric bud development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0001525

angiogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P16092
ensembl:ENSMUSP00000081041

P

Seeded From UniProt

complete

enables

GO:0004672

protein kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR008266

F

Seeded From UniProt

complete

enables

GO:0004713

protein tyrosine kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020635

F

Seeded From UniProt

complete

enables

GO:0005007

fibroblast growth factor-activated receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016248
InterPro:IPR028174

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR016248
InterPro:IPR017441

F

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR008266
InterPro:IPR016248
InterPro:IPR020635

P

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016248

P

Seeded From UniProt

complete

involved_in

GO:0008543

fibroblast growth factor receptor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016248

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016248

C

Seeded From UniProt

complete

enables

GO:0004714

transmembrane receptor protein tyrosine kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.10.1

F

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

PMID:20299672[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0003347

epicardial cell to mesenchymal cell transition

PMID:20299672[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0031410

cytoplasmic vesicle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0968

C

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0004713

protein tyrosine kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0829

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0091

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 Olivey, HE & Svensson, EC (2010) Epicardial-myocardial signaling directing coronary vasculogenesis. Circ. Res. 106 818-32 PubMed GONUTS page