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CHICK:CTHL3

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CATHL3
Protein Name(s) Cathelicidin-3

CATH-3 Fowlicidin-3

External Links
UniProt Q2IAL6
EMBL DQ092353
DQ092350
AB308318
UniGene Gga.51464
PDB 2HFR
PDBsum 2HFR
ProteinModelPortal Q2IAL6
SMR Q2IAL6
HOVERGEN HBG099601
InParanoid Q2IAL6
PhylomeDB Q2IAL6
EvolutionaryTrace Q2IAL6
Proteomes UP000000539
GO GO:0005576
GO:0016021
GO:0042742
GO:0045087
InterPro IPR001894
PANTHER PTHR10206
Pfam PF00666
ProDom PD001838

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0050830

defense response to Gram-positive bacterium

PMID:17229147[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0050829

defense response to Gram-negative bacterium

PMID:17229147[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0051673

membrane disruption in other organism

PMID:17229147[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010629

negative regulation of gene expression

PMID:17229147[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0061844

antimicrobial humoral immune response mediated by antimicrobial peptide

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:108443
PANTHER:PTN000024620
UniProtKB:P49913

P

Seeded From UniProt

complete

involved_in

GO:0050830

defense response to Gram-positive bacterium

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:108443
PANTHER:PTN000024620
RGD:1559878
UniProtKB:P22226
UniProtKB:P49913
UniProtKB:Q2IAL6
UniProtKB:Q2IAL7
UniProtKB:Q6QLQ5
UniProtKB:R4GJF1

P

Seeded From UniProt

complete

involved_in

GO:0050829

defense response to Gram-negative bacterium

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:108443
PANTHER:PTN000024620
RGD:1559878
UniProtKB:P22226
UniProtKB:Q2IAL6
UniProtKB:Q2IAL7
UniProtKB:Q6QLQ5
UniProtKB:R4GJF1

P

Seeded From UniProt

complete

involved_in

GO:0045087

innate immune response

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:108443
PANTHER:PTN000024620

P

Seeded From UniProt

complete

part_of

GO:0042581

specific granule

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:108443
PANTHER:PTN000024620
UniProtKB:P49913

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:105983
PANTHER:PTN000024620
RGD:1559878
UniProtKB:P49913

C

Seeded From UniProt

complete

enables

GO:0001530

lipopolysaccharide binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000024620
UniProtKB:Q2IAL7
UniProtKB:Q6QLQ5

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001894

C

Seeded From UniProt

complete

involved_in

GO:0006952

defense response

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001894

P

Seeded From UniProt

complete

involved_in

GO:0002376

immune system process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0391

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

involved_in

GO:0042742

defense response to bacterium

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0044

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0045087

innate immune response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0399

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Bommineni, YR et al. (2007) Fowlicidin-3 is an alpha-helical cationic host defense peptide with potent antibacterial and lipopolysaccharide-neutralizing activities. FEBS J. 274 418-28 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page