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CHICK:CP17A

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CYP17A1 (synonyms: CYP17)
Protein Name(s) Steroid 17-alpha-hydroxylase/17,20 lyase

17-alpha-hydroxyprogesterone aldolase CYPXVII Cytochrome P450 17A1 Cytochrome P450-C17 Cytochrome P450c17

External Links
UniProt P12394
EMBL M21406
PIR JT0318
RefSeq NP_001001901.1
UniGene Gga.834
ProteinModelPortal P12394
STRING 9031.ENSGALP00000013167
PaxDb P12394
GeneID 425056
KEGG gga:425056
CTD 1586
eggNOG COG2124
HOGENOM HOG000036991
HOVERGEN HBG106944
InParanoid P12394
KO K00512
PhylomeDB P12394
UniPathway UPA00062
NextBio 20827300
PRO PR:P12394
Proteomes UP000000539
GO GO:0016020
GO:0047442
GO:0020037
GO:0005506
GO:0004508
GO:0042446
GO:0006694
GO:0008202
Gene3D 1.10.630.10
InterPro IPR001128
IPR017972
IPR002401
Pfam PF00067
PRINTS PR00463
PR00385
SUPFAM SSF48264
PROSITE PS00086

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0042446

hormone biosynthetic process

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05093

P

Seeded From UniProt

complete

enables

GO:0020037

heme binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05093

F

Seeded From UniProt

complete

involved_in

GO:0008202

steroid metabolic process

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05093

P

Seeded From UniProt

complete

enables

GO:0004508

steroid 17-alpha-monooxygenase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05093

F

Seeded From UniProt

complete

enables

GO:0047442

17-alpha-hydroxyprogesterone aldolase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001209526
UniProtKB:P05093

F

Seeded From UniProt

complete

involved_in

GO:0042448

progesterone metabolic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001209526
UniProtKB:P05093

P

Seeded From UniProt

complete

involved_in

GO:0042446

hormone biosynthetic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001209526
UniProtKB:P05093

P

Seeded From UniProt

complete

enables

GO:0004508

steroid 17-alpha-monooxygenase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88586
PANTHER:PTN001209526
RGD:2456
UniProtKB:P05093
ZFIN:ZDB-GENE-040213-2

F

Seeded From UniProt

complete

enables

GO:0004508

steroid 17-alpha-monooxygenase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033282

F

Seeded From UniProt

complete

enables

GO:0005506

iron ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR036396

F

Seeded From UniProt

complete

involved_in

GO:0006694

steroid biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033282

P

Seeded From UniProt

complete

involved_in

GO:0007548

sex differentiation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033282

P

Seeded From UniProt

complete

enables

GO:0016705

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR017972
InterPro:IPR036396

F

Seeded From UniProt

complete

enables

GO:0020037

heme binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR033282
InterPro:IPR036396

F

Seeded From UniProt

complete

enables

GO:0047442

17-alpha-hydroxyprogesterone aldolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033282

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR017972
InterPro:IPR036396

P

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

involved_in

GO:0006694

steroid biosynthetic process

GO_REF:0000037
GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0755
UniPathway:UPA00062

P

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0004497

monooxygenase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0503

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page