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CHICK:CNTF

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CNTF (synonyms: CNF, GPA)
Protein Name(s) Ciliary neurotrophic factor

CNTF Growth-promoting activity GPA

External Links
UniProt Q02011
EMBL M80827
PIR JH0680
RefSeq NP_990823.1
UniGene Gga.48120
ProteinModelPortal Q02011
STRING 9031.ENSGALP00000011774
PaxDb Q02011
Ensembl ENSGALT00000043216
GeneID 396488
KEGG gga:396488
CTD 1270
eggNOG NOG114783
GeneTree ENSGT00420000029890
HOGENOM HOG000059605
HOVERGEN HBG005362
InParanoid Q02011
KO K05420
OMA KLWGLKV
PhylomeDB Q02011
NextBio 20816527
PRO PR:Q02011
Proteomes UP000000539
GO GO:0097058
GO:0005737
GO:0070120
GO:0040007
GO:0048644
GO:0043524
GO:0046533
GO:0048666
GO:0008284
GO:0042517
GO:0046668
Gene3D 1.20.1250.10
InterPro IPR009079
IPR012351
IPR000151
Pfam PF01110
SUPFAM SSF47266

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0070120

ciliary neurotrophic factor-mediated signaling pathway

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001432742
UniProtKB:P26441

P

Seeded From UniProt

complete

involved_in

GO:0048680

positive regulation of axon regeneration

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001432742
RGD:2370

P

Seeded From UniProt

complete

involved_in

GO:0048143

astrocyte activation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001432742
RGD:2370

P

Seeded From UniProt

complete

involved_in

GO:0043524

negative regulation of neuron apoptotic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001432742
RGD:2370
UniProtKB:P26441

P

Seeded From UniProt

complete

involved_in

GO:0042531

positive regulation of tyrosine phosphorylation of STAT protein

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88439
PANTHER:PTN001432742
RGD:2370
UniProtKB:P26441

P

Seeded From UniProt

complete

part_of

GO:0030424

axon

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001432742
RGD:2370

C

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88439
PANTHER:PTN001432742
RGD:2370

P

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001432742
UniProtKB:P26441

F

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88439
PANTHER:PTN001432742

C

Seeded From UniProt

complete

enables

GO:0005127

ciliary neurotrophic factor receptor binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001432742
RGD:2370

F

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001432742
RGD:2370

F

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

involved_in

GO:0070120

ciliary neurotrophic factor-mediated signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P26441
ensembl:ENSP00000355370

P

Seeded From UniProt

complete

enables

GO:0044877

protein-containing complex binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P26441
ensembl:ENSP00000355370

F

Seeded From UniProt

complete

involved_in

GO:0043524

negative regulation of neuron apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P26441
ensembl:ENSP00000355370

P

Seeded From UniProt

complete

involved_in

GO:0042531

positive regulation of tyrosine phosphorylation of STAT protein

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P26441
ensembl:ENSP00000355370

P

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P26441
ensembl:ENSP00000355370

P

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P26441
ensembl:ENSP00000355370

F

Seeded From UniProt

complete

enables

GO:0005138

interleukin-6 receptor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P26441
ensembl:ENSP00000355370

F

Seeded From UniProt

complete

involved_in

GO:0048666

neuron development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P51642
ensembl:ENSMUSP00000108555

P

Seeded From UniProt

complete

involved_in

GO:0048644

muscle organ morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P51642
ensembl:ENSMUSP00000108555

P

Seeded From UniProt

complete

involved_in

GO:0046668

regulation of retinal cell programmed cell death

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P51642
ensembl:ENSMUSP00000108555

P

Seeded From UniProt

complete

involved_in

GO:0046533

negative regulation of photoreceptor cell differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P51642
ensembl:ENSMUSP00000108555

P

Seeded From UniProt

complete

involved_in

GO:0042531

positive regulation of tyrosine phosphorylation of STAT protein

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P51642
ensembl:ENSMUSP00000108555

P

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P51642
ensembl:ENSMUSP00000108555

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P51642
ensembl:ENSMUSP00000108555

C

Seeded From UniProt

complete

enables

GO:0005127

ciliary neurotrophic factor receptor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000151

F

Seeded From UniProt

complete

involved_in

GO:0043524

negative regulation of neuron apoptotic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000151

P

Seeded From UniProt

complete

involved_in

GO:0070120

ciliary neurotrophic factor-mediated signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000151

P

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0339

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0007399

nervous system development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0524

P

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page