CHICK:CNOT7

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	CNOT7 (synonyms: CAF1)
Protein Name(s)	CCR4-NOT transcription complex subunit 7 CCR4-associated factor 1 CAF-1
External Links
UniProt	Q5ZJV9
EMBL	AJ720325
RefSeq	NP_001006454.1
UniGene	Gga.4905
ProteinModelPortal	Q5ZJV9
SMR	Q5ZJV9
STRING	9031.ENSGALP00000022159
PRIDE	Q5ZJV9
Ensembl	ENSGALT00000022198
GeneID	422733
KEGG	gga:422733
CTD	29883
eggNOG	COG5228
GeneTree	ENSGT00390000000080
HOGENOM	HOG000173077
HOVERGEN	HBG051044
InParanoid	Q5ZJV9
KO	K12581
OMA	KYSGHLY
OrthoDB	EOG74BJSP
PhylomeDB	Q5ZJV9
TreeFam	TF314185
NextBio	20825324
PRO	PR:Q5ZJV9
Proteomes	UP000000539
GO	GO:0030014 GO:0000932 GO:0016020 GO:0005634 GO:0000175 GO:0004532 GO:0046872 GO:0004535 GO:0003723 GO:0033962 GO:0000290 GO:0043928 GO:0031047 GO:0008285 GO:0000289 GO:0008284 GO:1900153 GO:0060213 GO:0045944 GO:0006417 GO:0090503 GO:0006351
Gene3D	3.30.420.10
InterPro	IPR006941 IPR012337
Pfam	PF04857
SUPFAM	SSF53098

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UIV1	P		Seeded From UniProt	complete
involved_in	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UIV1	P		Seeded From UniProt	complete
involved_in	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UIV1	P		Seeded From UniProt	complete
involved_in	GO:0031047	gene silencing by RNA	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q60809	P		Seeded From UniProt	complete
part_of	GO:0030014	CCR4-NOT complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UIV1	C		Seeded From UniProt	complete
involved_in	GO:0008285	negative regulation of cell population proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UIV1	P		Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UIV1	P		Seeded From UniProt	complete
enables	GO:0004535	poly(A)-specific ribonuclease activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UIV1	F		Seeded From UniProt	complete
enables	GO:0004532	exoribonuclease activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UIV1	F		Seeded From UniProt	complete
enables	GO:0000175	3'-5'-exoribonuclease activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UIV1	F		Seeded From UniProt	complete
involved_in	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000084083 UniProtKB:Q9UFF9 UniProtKB:Q9UIV1	P		Seeded From UniProt	complete
part_of	GO:0030015	CCR4-NOT core complex		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000084083 PomBase:SPCC18.06c SGD:S000005335	C		Seeded From UniProt	complete
involved_in	GO:0017148	negative regulation of translation		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0036239 PANTHER:PTN000084083	P		Seeded From UniProt	complete
enables	GO:0004535	poly(A)-specific ribonuclease activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0036239 MGI:MGI:1298230 PANTHER:PTN000084083 PomBase:SPCC18.06c UniProtKB:Q9UFF9 UniProtKB:Q9UIV1	F		Seeded From UniProt	complete
part_of	GO:0000932	P-body		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1298230 PANTHER:PTN000084083 SGD:S000005335 WB:WBGene00000369	C		Seeded From UniProt	complete
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004527	P		Seeded From UniProt	complete
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004518	P		Seeded From UniProt	complete
involved_in	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0000175	P		Seeded From UniProt	complete
involved_in	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0000175	P		Seeded From UniProt	complete
involved_in	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004535	P		Seeded From UniProt	complete
involved_in	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004535	P		Seeded From UniProt	complete
involved_in	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004535	P		Seeded From UniProt	complete
involved_in	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004535	P		Seeded From UniProt	complete
involved_in	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004535	P		Seeded From UniProt	complete
involved_in	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60809 ensembl:ENSMUSP00000117304	P		Seeded From UniProt	complete
involved_in	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60809 ensembl:ENSMUSP00000117304	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60809 ensembl:ENSMUSP00000117304	P		Seeded From UniProt	complete
involved_in	GO:0033962	cytoplasmic mRNA processing body assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60809 ensembl:ENSMUSP00000117304	P		Seeded From UniProt	complete
involved_in	GO:0031047	gene silencing by RNA	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60809 ensembl:ENSMUSP00000117304	P		Seeded From UniProt	complete
part_of	GO:0030014	CCR4-NOT complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60809 ensembl:ENSMUSP00000117304	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60809 ensembl:ENSMUSP00000117304	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60809 ensembl:ENSMUSP00000117304	C		Seeded From UniProt	complete
enables	GO:0004535	poly(A)-specific ribonuclease activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60809 ensembl:ENSMUSP00000117304	F		Seeded From UniProt	complete
part_of	GO:0000932	P-body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60809 ensembl:ENSMUSP00000117304	C		Seeded From UniProt	complete
involved_in	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60809 ensembl:ENSMUSP00000117304	P		Seeded From UniProt	complete
involved_in	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60809 ensembl:ENSMUSP00000117304	P		Seeded From UniProt	complete
involved_in	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	P		Seeded From UniProt	complete
part_of	GO:0075341	host cell PML body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	C		Seeded From UniProt	complete
involved_in	GO:0061014	positive regulation of mRNA catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	P		Seeded From UniProt	complete
involved_in	GO:0060339	negative regulation of type I interferon-mediated signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	P		Seeded From UniProt	complete
involved_in	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	P		Seeded From UniProt	complete
involved_in	GO:0051607	defense response to virus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	P		Seeded From UniProt	complete
involved_in	GO:0045070	positive regulation of viral genome replication	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	P		Seeded From UniProt	complete
involved_in	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	P		Seeded From UniProt	complete
involved_in	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	P		Seeded From UniProt	complete
part_of	GO:0030014	CCR4-NOT complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	C		Seeded From UniProt	complete
part_of	GO:0016607	nuclear speck	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	C		Seeded From UniProt	complete
part_of	GO:0016604	nuclear body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	C		Seeded From UniProt	complete
involved_in	GO:0010629	negative regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	P		Seeded From UniProt	complete
involved_in	GO:0008285	negative regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	P		Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	P		Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	C		Seeded From UniProt	complete
enables	GO:0004535	poly(A)-specific ribonuclease activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	F		Seeded From UniProt	complete
enables	GO:0004532	exoribonuclease activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	F		Seeded From UniProt	complete
enables	GO:0003714	transcription corepressor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	F		Seeded From UniProt	complete
enables	GO:0000175	3'-5'-exoribonuclease activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	F		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UIV1 ensembl:ENSP00000355279	P		Seeded From UniProt	complete
enables	GO:0000175	3'-5'-exoribonuclease activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR039636	F		Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR036397	F		Seeded From UniProt	complete
enables	GO:0004535	poly(A)-specific ribonuclease activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR039636 InterPro:IPR039637	F		Seeded From UniProt	complete
part_of	GO:0030014	CCR4-NOT complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR039637	C		Seeded From UniProt	complete
enables	GO:0004535	poly(A)-specific ribonuclease activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.1.13.4	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0694	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0004518	nuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0540	F		Seeded From UniProt	complete
involved_in	GO:0031047	gene silencing by RNA	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0943	P		Seeded From UniProt	complete
enables	GO:0004527	exonuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0269	F		Seeded From UniProt	complete
involved_in	GO:0006417	regulation of translation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0810	P		Seeded From UniProt	complete
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References

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