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CHICK:CASP2

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CASP2 (synonyms: ICH1)
Protein Name(s) Caspase-2

CASP-2 ICH-1L/1S Protease ICH-1 Caspase-2 subunit p18 Caspase-2 subunit p13 Caspase-2 subunit p12

External Links
UniProt Q98943
EMBL U64963
RefSeq NP_001161173.1
UniGene Gga.504
ProteinModelPortal Q98943
SMR Q98943
STRING 9031.ENSGALP00000029853
MEROPS C14.006
PaxDb Q98943
PRIDE Q98943
GeneID 395857
KEGG gga:395857
CTD 835
eggNOG NOG305976
HOGENOM HOG000290714
HOVERGEN HBG103962
InParanoid Q98943
KO K02186
PhylomeDB Q98943
BRENDA 3.4.22.55
NextBio 20815924
PRO PR:Q98943
Proteomes UP000000539
GO GO:0004197
GO:0006915
GO:0042981
Gene3D 1.10.533.10
3.40.50.1460
InterPro IPR001315
IPR029030
IPR017350
IPR011029
IPR011600
IPR001309
IPR016129
IPR002138
IPR015917
Pfam PF00619
PF00656
PIRSF PIRSF038001
PRINTS PR00376
SMART SM00114
SM00115
SUPFAM SSF47986
PROSITE PS50209
PS01122
PS01121
PS50207
PS50208

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0097192

extrinsic apoptotic signaling pathway in absence of ligand

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97295
PANTHER:PTN000048135

P

Seeded From UniProt

complete

enables

GO:0097153

cysteine-type endopeptidase activity involved in apoptotic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0019972
MGI:MGI:107739
MGI:MGI:109383
MGI:MGI:1261423
MGI:MGI:97295
PANTHER:PTN000047947
UniProtKB:P42574
UniProtKB:Q14790

F

Seeded From UniProt

complete

involved_in

GO:0006915

apoptotic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010501
FB:FBgn0020381
FB:FBgn0026404
FB:FBgn0028381
FB:FBgn0033659
MGI:MGI:107739
MGI:MGI:109383
MGI:MGI:1261423
MGI:MGI:1277950
MGI:MGI:1312922
PANTHER:PTN000047947
RGD:2274
RGD:2275
RGD:61867
RGD:620945
RGD:69274
UniProtKB:O15519
UniProtKB:P42574
UniProtKB:P55210
UniProtKB:P55211
UniProtKB:Q14790
WB:WBGene00000417

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0019972
FB:FBgn0020381
FB:FBgn0026404
FB:FBgn0028381
FB:FBgn0033051
MGI:MGI:107739
MGI:MGI:1261423
MGI:MGI:1336166
MGI:MGI:97295
PANTHER:PTN000047947
RGD:2274
RGD:2275
RGD:61867
RGD:620945
RGD:70967
UniProtKB:O15519
UniProtKB:P31944
UniProtKB:Q95ND5
UniProtKB:Q9ULZ3
WB:WBGene00000417

C

Seeded From UniProt

complete

involved_in

GO:0097194

execution phase of apoptosis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0097200

P

Seeded From UniProt

complete

enables

GO:0004197

cysteine-type endopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001309
InterPro:IPR002138
InterPro:IPR002398

F

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001309
InterPro:IPR002138
InterPro:IPR002398

P

Seeded From UniProt

complete

enables

GO:0008234

cysteine-type peptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015917

F

Seeded From UniProt

complete

involved_in

GO:0042981

regulation of apoptotic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001315

P

Seeded From UniProt

complete

enables

GO:0097200

cysteine-type endopeptidase activity involved in execution phase of apoptosis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR035702

F

Seeded From UniProt

complete

involved_in

GO:0006915

apoptotic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0053

P

Seeded From UniProt

complete

enables

GO:0008234

cysteine-type peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0788

F

Seeded From UniProt

complete

enables

GO:0008233

peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

F

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page